Clinical, Histopathological, and Virological Evaluation of 203 Patients With a Clinical Diagnosis of Molluscum Contagiosum-Reference-Cited by-同舟云学术

Clinical, Histopathological, and Virological Evaluation of 203 Patients With a Clinical Diagnosis of Molluscum Contagiosum

Published:2018-11-01 Issue:11 Volume:5 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Trčko Katarina¹,Hošnjak Lea²,Kušar Blanka²,Zorec Tomaž Mark²,Kocjan Boštjan J²,Križmarić Miljenko³⁴,Seme Katja²,Miljković Jovan³,Luzar Boštjan⁵,Poljak Mario²

Affiliation:

1. Department of Dermatovenereology, University Medical Centre Maribor, Slovenia

2. Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Slovenia

3. Faculty of Medicine, University of Maribor, Slovenia

4. Faculty of Health Sciences, University of Maribor, Slovenia

5. Institute of Pathology, Faculty of Medicine, University of Ljubljana, Slovenia

Abstract

Abstract Molluscum contagiosum (MC) manifests as small, umbilicated papules caused by the molluscum contagiosum virus (MCV). The extent of clinical misdiagnosis of MC is unknown. Combined clinical, histopathological, and virological evaluation of 203 consecutive patients with clinical diagnosis of MC treated at a university hospital during a 5-year period showed the correct clinical diagnosis in 188 of 203 (92.6%) patients. All 15 clinically misdiagnosed MC lesions were histopathologically and virologically confirmed as either common or anogenital warts caused by different human papillomaviruses. The MCV1/MCV2 subtypes ratio was 1.54:1, and the distribution of MCV subtypes differed across patients’ age and anatomical location of lesions.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/article-pdf/5/11/ofy298/33629722/ofy298.pdf

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