Cryptococcal Meningitis and Tuberculous Meningitis Co-infection in HIV-Infected Ugandan Adults-Reference-Cited by-同舟云学术

Cryptococcal Meningitis and Tuberculous Meningitis Co-infection in HIV-Infected Ugandan Adults

Published:2018-08-01 Issue:8 Volume:5 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Ellis Jayne¹²,Cresswell Fiona V¹³,Rhein Joshua¹⁴,Ssebambulidde Kenneth¹,Boulware David R⁴

Affiliation:

1. Infectious Diseases Institute, College of Health Sciences, Makerere University Kampala, Kampala, Uganda

2. Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London, United Kingdom

3. Clinical Research Department, London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom

4. Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis

Abstract

Abstract We report 5 HIV-infected Ugandan adults with cryptococcal and tuberculous (TB) meningitis co-infection. All unmasked meningitis occurred within 5 weeks of starting HIV therapy. Xpert MTB/RIF Ultra facilitated prompt diagnosis; however, 60% in-hospital mortality occurred. TB meningitis coinfection prevalence was 0.8% (5/586) among cryptococcal meningitis, 2 during second cryptococcal episodes.

Funder

National Institute of Neurological Disorders and Stroke

Fogarty International Center

National Institute of Allergy and Infectious Diseases

United Kingdom Medical Research Council

Wellcome Trust

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/article-pdf/5/8/ofy193/33578500/ofy193.pdf