Time Course of C-Reactive Protein and Procalcitonin Levels During the Treatment of Acute Bacterial Skin Infections-Reference-Cited by-同舟云学术

Time Course of C-Reactive Protein and Procalcitonin Levels During the Treatment of Acute Bacterial Skin Infections

Published:2018-01-30 Issue:3 Volume:5 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Jenkins Timothy C¹²³⁴⁵,Haukoos Jason S⁶⁷,Cotton Eleanor⁸,Weitzenkamp David⁸,Frank Daniel N⁵,Burman William J¹²⁹⁴⁵

Affiliation:

1. Department of Medicine, Denver Health, Denver, Colorado

2. Division of Infectious Diseases, Denver Health, Denver, Colorado

3. Department of Patient Safety and Quality, Denver Health, Denver, Colorado

4. Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado

5. Division of Infectious Diseases, University of Colorado School of Medicine, Aurora, Colorado

6. Department of Emergency Medicine, Denver Health, Denver, Colorado

7. Department of Emergency Medicine, University of Colorado School of Medicine, Aurora, Colorado

8. Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, Colorado

9. Denver Public Health, Denver Health, Denver, Colorado

Abstract

Abstract In a pilot study of 22 patients with an acute bacterial skin infection, serum levels of C-reactive protein and procalcitonin tended to be elevated at presentation and declined within 3–5 days of treatment. Further study of a biomarker-guided treatment strategy to reduce antibiotic overuse in skin infections is warranted.

Funder

National Institutes of Health

National Center for Advancing Translational Sciences

Colorado Clinical and Translational Sciences Institute

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/article-pdf/5/3/ofy029/33575497/ofy029.pdf

Reference12 articles.

1. Antibiotic prescribing practices in a multicenter cohort of patients hospitalized for acute bacterial skin and skin structure infection;Jenkins;Infect Control Hosp Epidemiol,2014