Double Infection With Leishmania tropica and L. major in an HIV Patient Controlled With High Doses of Amphotericin B

Author:

Al Balushi Asma1,Khamis Faryal1,Klaassen Corné H W2,Gangneux Jean-Pierre3,Van Hellemond Jaap J2,Petersen Eskild1

Affiliation:

1. Department of Infectious Diseases, The Royal Hospital, Muscat, Sultanate of Oman

2. Department of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center, Rotterdam, the Netherlands

3. Centre Hospitalier Universitaire Pontchaillou, Rennes, France

Abstract

Abstract We present a unique case of disseminated Leishmaniasis in an HIV patient. Two different Leishmania species were identified by genomic sequencing in both bone marrow and skin. The Leishmania infection could be suppressed but not cured, despite a high dose of amphotericin B of nearly 65 g over more than 6 years.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Reference14 articles.

1. Visceral leishmaniosis in immunocompromised host: an update and literature review;Pagliano;J Chemother,2017

2. Drug resistance and treatment failure in leishmaniasis: a 21st century challenge;Ponte-Sucre;PLoS Negl Trop Dis,2017

3. Rapid diagnosis of leishmaniasis by fluorogenic polymerase chain reaction;Wortmann;Am J Trop Med Hyg,2001

4. Evaluation of four single-locus markers for Leishmania species discrimination by sequencing;Van der Auwera;J Clin Microbiol,2014

5. Leishmaniasis-HIV coinfection: current challenges;Lindoso;HIV AIDS (Auckl),2016

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