Assessment of pre-donation glomerular filtration rate: going back to basics

Author:

Mariat Christophe1,Mjøen Geir2,Watschinger Bruno3,Sever Mehmet Sukru4,Crespo Marta5,Peruzzi Licia6,Oniscu Gabriel C7,Abramowicz Daniel8,Hilbrands Luuk9ORCID,Maggiore Umberto10ORCID

Affiliation:

1. Service de Néphrologie, Dialyse et Transplantation Rénale, Centre Hospitalier Universitaire de Saint Etienne, Hôpital NORD, Université de LYON, Université Jean MONNET, Saint Etienne, France

2. Oslo University Hospital, Oslo, Norway

3. Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria

4. Istanbul School of Medicine, Istanbul, Turkey

5. Nephrology Department, Hospital del Mar, Barcelona, Spain

6. Pediatric Nephrology, Turin, Italy

7. Edinburgh Transplant Centre, Edinburgh, UK

8. Antwerp University Hospital, Antwerp, Belgium

9. Department of Nephrology, Radboud University Medical Center, Nijmegen, The Netherlands

10. Department of Medicine and Surgery, University of Parma, Parma, Italy

Abstract

Abstract The 2017 version of the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines is the most recent international framework for the evaluation and care of living kidneys donors. Along with the call for an integrative approach evaluating the long-term end-stage kidney disease risk for the future potential donor, several recommendations are formulated regarding the pre-donation glomerular filtration rate (GFR) adequacy with no or little consideration for the donor candidate’s age or for the importance of using reference methods of GFR measurements. Herein, we question the position of the KDIGO guidelines and discuss the rationale and modalities for a more basic, but no less demanding GFR evaluation enabling a more efficient selection of potential kidney donors.

Publisher

Oxford University Press (OUP)

Subject

Transplantation,Nephrology

Reference56 articles.

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4. KDIGO clinical practice guideline on the evaluation and care of living kidney donors;Lentine;Transplantation,2017

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