The RECOVAC IR study: the immune response and safety of the mRNA-1273 COVID-19 vaccine in patients with chronic kidney disease, on dialysis or living with a kidney transplant

Author:

Kho Marcia M L1,Reinders Marlies E J1,Baan Carla C1,van Baarle Debbie23,Bemelman Frederike J4,Diavatopoulos Dimitri A5,Gansevoort Ron T6,van der Klis Fiona R M3,Koopmans Marion P G7,Messchendorp A Lianne6,van der Molen Renate G8,Remmerswaal Ester B M9,Rots Nynke3,Vart Priya61011,de Vries Rory D7,Hilbrands Luuk B12ORCID,Sanders Jan-Stephan F6,Abrahams A C,Hemmelder M H,ten Dam M A G J,de Vries A P J,van Binnendijk R S,den Hartog G,Bouwmans P,Frolke S,Malahé S R K,

Affiliation:

1. Department of Internal Medicine, Erasmus Medical Center Transplant Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands

2. Department of Medical Microbiology and Infection Prevention, University Medical Center Groningen, Groningen, The Netherlands

3. Center for Infectious Diseases Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands

4. Renal Transplant Unit, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands

5. Department of Laboratory Medicine, Laboratory of Medical Immunology, Section Pediatric Infectious Diseases, Radboud Institute for Molecular Life Sciences, Radboud Center for Infectious Diseases, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands

6. Division of Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

7. Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands

8. Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands

9. Department of Experimental Immunology, Amsterdam University Medical Center, Amsterdam Infection and Immunity Institute, University of Amsterdam, Amsterdam, The Netherlands

10. Department of Health Evidence, Radboud University Medical Center, Radboud University, Nijmegen, The Netherlands

11. Department of Cardiology, Radboud University Medical Center, Radboud University, Nijmegen, The Netherlands

12. Department of Nephrology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands

Funder

Netherlands Organization for Health Research and Development

Publisher

Oxford University Press (OUP)

Subject

Transplantation,Nephrology

Reference15 articles.

1. Factors associated with COVID-19-related death using OpenSAFELY;Williamson;Nature,2020

2. COVID-19-related mortality in kidney transplant and dialysis patients: results of the ERACODA collaboration;Hilbrands;Nephrol Dial Transplant,2020

3. Vaccination in chronic kidney disease;Reddy;Adv Chronic Kidney Dis,2019

4. Weak anti-SARS-CoV-2 antibody response after the first injection of an mRNA COVID-19 vaccine in kidney transplant recipients;Benotmane;Kidney Int,2021

5. Impaired humoral and cellular immunity after SARS-CoV2 BNT162b2 (Tozinameran) prime-boost vaccination in kidney transplant recipients;Sattler;medRxiv,2021

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