Overexpression of HMG-CoA synthase promotes Arabidopsis root growth and adversely affects glucosinolate biosynthesis

Author:

Liao Pan12,Lung Shiu-Cheung1,Chan Wai Lung1,Bach Thomas J3,Lo Clive1,Chye Mee-Len12ORCID

Affiliation:

1. School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong, China

2. State Key Laboratory of Agrobiotechnology, CUHK, Shatin, Hong Kong, China

3. Centre National de la Recherche Scientifique, UPR 2357, Institut de Biologie Moléculaire des Plantes, Université de Strasbourg, Strasbourg, France

Abstract

Inhibition of 3-hydroxy-3-methylglutaryl-CoA synthase (HMGS) retarded root growth in Arabidopsis seedlings by reducing stigmasterol, auxin, and cytokinin levels. Differentially expressed proteins and metabolite changes revealed a relationship between HMGS and glucosinolate biosynthesis.

Funder

Wilson and Amelia Wong Endowment Fund

Research Grants Council of Hong Kong

Innovation Technology Fund of Innovation Technology Commission

State Key Laboratories in Hong Kong and HKU CRCG

Publisher

Oxford University Press (OUP)

Subject

Plant Science,Physiology

Reference108 articles.

1. Sulfur deficiency-induced repressor proteins optimize glucosinolate biosynthesis in plants;Aarabi;Science Advances,2016

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3. Expression of Brassica juncea 3-hydroxy-3-methylglutaryl CoA synthase is developmentally regulated and stress-responsive;Alex;The Plant Journal,2000

4. An alternative cytokinin biosynthesis pathway;Åstot;Proceedings of the National Academy of Sciences, USA,2000

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