CD20 positivity and white blood cell count predict treatment outcomes in Philadelphia chromosome-negative acute lymphoblastic leukemia patients ineligible for pediatric-inspired chemotherapy

Author:

Isshiki Yusuke12,Ohwada Chikako2,Sakaida Emiko2,Onoda Masahiro1,Aotsuka Nobuyuki3,Tanaka Hiroaki4,Fukazawa Motoharu5,Cho Ryuko6,Sugawara Takeaki7,Kawaguchi Takeharu8,Hara Satoru9,Yokota Akira1

Affiliation:

1. Department of Hematology, Chiba Aoba Municipal Hospital

2. Department of Hematology, Chiba University Hospital

3. Department of Hematology and Oncology, Japanese Red Cross Narita Hospital

4. Department of Hematology, Asahi General Hospital

5. Department of Internal Medicine, JCHO Funabashi Central Hospital

6. Department of Hematology, Chibaken Saiseikai Narashino Hospital

7. Department of Hematology and Oncology, Chiba Cancer Center

8. Department of Hematology, Oami Municipal Hospital

9. Department of Hematology, Chiba Rosai Hospital, Japan

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Radiology Nuclear Medicine and imaging,Oncology,General Medicine

Reference25 articles.

1. Allogeneic bone marrow transplantation in adult acute lymphoblastic leukemia in first complete remission: a comparative study. French Group of Therapy of Adult Acute Lymphoblastic Leukemia;Sebban;J Clin Oncol,1994

2. Outcome of treatment in adults with acute lymphoblastic leukemia: analysis of the LALA-94 trial;Thomas;J Clin Oncol,2004

3. Better outcome of adult acute lymphoblastic leukemia after early genoidentical allogeneic bone marrow transplantation (BMT) than after late high-dose therapy and autologous BMT: a GOELAMS trial;Hunault;Blood,2004

4. In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolidation/maintenance chemotherapy in all patients: final results of the International ALL Trial (MRC UKALL XII/ECOG E2993);Goldstone;Blood,2008

5. Myeloablative allogeneic versus autologous stem cell transplantation in adult patients with acute lymphoblastic leukemia in first remission: a prospective sibling donor versus no-donor comparison;Cornelissen;Blood,2009

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