Two challenging cases of anti-MDA-5 dermatomyositis with rapidly progressive interstitial lung disease-Reference-Cited by-同舟云学术

Two challenging cases of anti-MDA-5 dermatomyositis with rapidly progressive interstitial lung disease

Published:2024-06-01 Issue:6 Volume:2024 Page:
ISSN:2053-8855
Container-title:Oxford Medical Case Reports
language:en
Short-container-title:

Author:

Biddle Kathryn¹²^ORCID,Agaoglu Elif³,Brent Geoffrey⁴,Adam John⁵^ORCID,Nockels Rachel⁵,Loveridge Adam³,Bazari Farid³,Natkunarajah Janakan⁴,Al-Shakarchi Israa²

Affiliation:

1. St George's University of London , Infection and Immunity, Cranmer Terrace, London, SW17 0RE, UK

2. Kingston Hospital NHS Foundation Trust , Rheumatology, Kingston upon Thames, KT2 7QB, UK

3. Kingston Hospital NHS Foundation Trust , Respiratory, Kingston upon Thames, KT2 7QB, UK

4. Kingston Hospital NHS Foundation Trust , Dermatology, Kingston upon Thames, KT2 7QB, UK

5. Kingston Hospital NHS Foundation Trust , General Medicine, Kingston upon Thames, KT2 7QB, UK

Abstract

Abstract Anti-MDA-5 dermatomyositis (DM) is a subtype of idiopathic inflammatory myopathy, commonly presenting as clinically amyopathic dermatomyositis. It is associated with rapidly progressive interstitial lung disease and a poor prognosis. Here, we present two cases of anti-MDA-5 DM and discuss the challenges associated with timely diagnosis, and the importance of early and aggressive treatment.

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/omcr/article-pdf/2024/6/omae061/58161761/omae061.pdf

Reference9 articles.

1. Idiopathic inflammatory myopathies: a review;Ashton;Intern Med J,2021

2. Myositis-specific autoantibodies: an important tool to support diagnosis of myositis;Betteridge;J Intern Med,2016

3. Understanding and managing anti-MDA 5 dermatomyositis, including potential COVID-19 mimicry;Mehta;Rheumatol Int,2021

4. Distinct profiles of myositis-specific autoantibodies in Chinese and Japanese patients with polymyositis/dermatomyositis;Chen;Clin Rheumatol,2015

5. Autoantibodies to a 140-kd polypeptide, CADM-140, in Japanese patients with clinically amyopathic dermatomyositis;Sato;Arthritis Rheum,2005

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Anti-melanoma Differentiation-Associated Gene 5 (Anti-MDA5) Dermatomyositis-Associated Interstitial Lung Disease Complicated by Pneumomediastinum: A Case Report and Literature Review;Cureus;2024-07-09