Complete resolution of a giant multilocular prostatic cystadenoma following androgen deprivation therapy: an illustrative case report

Author:

Sushentsev Nikita1,Rimmer Yvonne2,Barrett Tristan1

Affiliation:

1. Department of Radiology, Addenbrooke’s Hospital and University of Cambridge, Cambridge CB2 0QQ, UK

2. Department of Oncology, Addenbrooke’s Hospital and University of Cambridge, Cambridge CB2 0QQ, UK

Abstract

ABSTRACT Giant multilocular prostatic cystadenoma (GMPC) is a rare benign pelvic mass for which complete surgical resection is an accepted treatment of choice. This report presents the first case of complete resolution of GMPC following a 3-year course of luteinising hormone-releasing hormone agonist alongside external beam radiotherapy for the concurrent treatment of unfavorable intermediate-risk prostate cancer. In addition to illustrating the imaging features of the effect of androgen deprivation therapy (ADT) and radiotherapy on GMPC regression, this case provides evidence for considering ADT as an alternative, noninvasive GMPC treatment option in patients in whom surgical treatment is either contraindicated or can be made less invasive by reducing the size of GMPC prior to its removal.

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,Developmental Biology,Embryology,Anatomy

Reference8 articles.

1. Giant multilocular prostatic cystadenoma;Nakamura;World J Surg Oncol,2019

2. Giant multilocular prostatic cystadenoma: a distinctive lesion of the retroperitoneum in men. A report of two cases;Maluf;Am J Surg Pathol,1991

3. Giant multilocular cystadenoma of the prostate responsive to GnRH antagonists;Datta;Urology,2003

4. Giant multilocular prostatic cystadenoma in a 16-year-old male with difficulty in defecation: case report and literature review;Kong;Int J Clin Exp Pathol,2020

5. Multimodality approach to imaging giant multilocular cystadenoma of the prostate: a rare entity;El-Asmar;Radiol Case Reports,2019

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