Rectal gastrointestinal stromal tumor (GIST) in a patient with Crohn’s disease: a rare coincidence case report and brief literature review

Author:

Sadeghi Amir1,Moghadam Pardis Ketabi1ORCID,Mangeli Forough2,Mohammadi Mahsa1,Ghadirzadeh Erfan3ORCID,Rajabnia Mohsen4ORCID

Affiliation:

1. Shahid Beheshti University of Medical Sciences Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, , Tehran province, Tehran, Iran

2. Shahid Beheshti University of Medical Sciences Clinical Pathologist, Department of Pathology, School of Medicine, , Tehran province, Tehran, Iran

3. Mazandaran University of Medical Sciences Gut and Liver Research Center, Non-communicable Diseases Institute, , Mazandaran province, Sari, Iran

4. Alborz University of Medical Sciences Non-Communicable Diseases Research Center, , Alborz province, Karaj, Iran

Abstract

Abstract Gastrointestinal stromal tumors (GISTs) are the most common type of gastrointestinal mesenchymal tumors. The most common site for developing these neoplasms is the stomach and small intestine. In contrast, anorectal GISTs are very rare. Population-based studies have shown an increased risk of colorectal cancers (CRC) in patients with Crohn’s disease (CD). As in sporadic CRC, adenocarcinomas are the most commonly observed tumor. Accordingly, it is expected that rectal mass in CD patients to be an adenocarcinoma. Some reports have presented CD cases with GISTs along the gastrointestinal tract; however, to the best of our knowledge, a rectal GIST has not been reported in CD. Herein, we report a 41-year-old woman with CD who presented with 8 weeks of constipation and was diagnosed with rectal GIST and briefly review existing reports regarding GIST in IBD.

Publisher

Oxford University Press (OUP)

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