Single-nucleus transcriptomics reveals adrenergic and STAT3 signalling in paradoxical low-flow low-gradient-specific cardiomyocyte subclusters: implications for aortic stenosis pathogenesis and treatment-Reference-Cited by-同舟云学术

Single-nucleus transcriptomics reveals adrenergic and STAT3 signalling in paradoxical low-flow low-gradient-specific cardiomyocyte subclusters: implications for aortic stenosis pathogenesis and treatment

Published:2024-06-29 Issue: Volume: Page:
ISSN:0008-6363
Container-title:Cardiovascular Research
language:en
Short-container-title:

Author:

Xu Xingbo¹²^ORCID,Tan Xiaoying²³,Cui Baolong¹²,Paul Niels B¹⁴,Elkenani Manar¹²,Beuthner Bo E¹²,Li Weichao¹²,Mohamed Belal A¹²,Schnelle Moritz²⁵,Puls Miriam¹²^ORCID,Zeisberg Elisabeth M¹²,Zeisberg Michael³,Beißbarth Tim⁴,Toischer Karl¹²,Hasenfuß Gerd¹²

Affiliation:

1. Clinic for Cardiology and Pulmonology, University Medical Center Göttingen , Robert-Koch-Str. 40, 37075 Göttingen , Germany

2. German Center for Cardiovascular Research (DZHK), Partner Site Göttingen , Robert-Koch-Str. 42a, 37075 Göttingen , Germany

3. Department of Nephrology and Rheumatology, University Medical Center Göttingen , Robert-Koch-Str. 40, 37075 Göttingen , Germany

4. Department of Medical Bioinformatics, University Medical Center Göttingen , Goldschmidtstraße 1, 37077 Göttingen , Germany

5. Department of Clinical Chemistry, University Medical Center Göttingen , Robert-Koch-Str. 40, 37075 Göttingen , Germany

Funder

German Research Foundation (DFG) Cluster of Excellence

Deutsches Zentrum für Herz Kreislauf-Forschung

Deutsche Stiftung für Herzforschung

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/cardiovascres/advance-article-pdf/doi/10.1093/cvr/cvae137/58513726/cvae137.pdf

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2. Current management of calcific aortic stenosis;Lindman;Circ Res,2013

3. Predictors of mortality and outcomes of therapy in low-flow severe aortic stenosis: a Placement of Aortic Transcatheter Valves (PARTNER) trial analysis;Herrmann;Circulation,2013

4. TAVI in patients with low-flow low-gradient aortic stenosis—short-term and long-term outcomes;Steffen;Clin Res Cardiol,2022

5. Cells of the adult human heart;Litvinukova;Nature,2020