Zilebesiran, a ribonucleic acid interference agent targeting angiotensinogen, proves a promising approach in hypertension
Author:
Affiliation:
1. Centre for Cardiovascular Science, The Queen’s Medical Research Institute, The University of Edinburgh , 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland , UK
Publisher
Oxford University Press (OUP)
Link
https://academic.oup.com/cardiovascres/article-pdf/120/10/e41/58996968/cvae140.pdf
Reference13 articles.
1. Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants;NCD Risk Factor Collaboration (NCD-RisC);Lancet,2021
2. Adherence in hypertension;Burnier;Circ Res,2019
3. Small interfering RNA: discovery, pharmacology and clinical development—an introductory review;Ranasinghe;Brit J Pharmacol,2023
4. Two phase 3 trials of inclisiran in patients with elevated LDL cholesterol;Ray;N Engl J Med,2020
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