Comparison of the average surviving fraction model with the integral biologically effective dose model for an optimal irradiation scheme

Author:

Takagi Ryo1,Komiya Yuriko2,Sutherland Kenneth L3,Shirato Hiroki34,Date Hiroyuki5,Mizuta Masahiro2

Affiliation:

1. Graduate School of Information Science and Technology, Hokkaido University, Kita-14, Nishi-9, Kita-ku, Sapporo, 060-0814, Japan

2. Laboratory of Advanced Data Science, Information Initiative Center, Hokkaido University, Kita-11, Nishi-5, Kita-ku, Sapporo, 060-0811, Japan

3. Global Station for Quantum Medical Science and Engineering, Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido University, Kita-15, Nishi-8, Kita-ku, Sapporo, 060-0815, Japan

4. Department of Radiation Medicine, Faculty of Medicine, Hokkaido University, Kita-15, Nishi-7, Kita-ku, Sapporo, 060-8638, Japan

5. Faculty of Health Sciences, Hokkaido University, Kita-12, Nishi-5, Kita-ku, Sapporo, 060-0812, Japan

Funder

Japan Society for the Promotion of Science (JSPS)

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Radiology, Nuclear Medicine and imaging,Radiation

Reference30 articles.

1. 21 years of biologically effective dose;Fowler;Br J Radiol,2010

2. The integral biologically effective dose to predict brain stem toxicity of hypofractionated stereotactic radiotherapy;Clark;Int J Radiat Oncol Biol Phys,1998

3. The dependence of optimal fractionation schemes on the spatial dose distribution;Unkelbach;Phys Med Biol,2013

4. Optimal fractionation in radiotherapy with multiple normal tissues;Saberian;Math Med Biol,2016

5. Implications of nonuniform tumor doses for radioimmunotherapy;O’Donoghue;J Nucl Med,1999

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