Dissecting PUGNAc-mediated inhibition of the pro-survival action of insulin
Author:
Affiliation:
1. Department of Biochemistry and Molecular Biology
2. Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA 30602-1516, USA
Funder
National Institutes of Health
National Institute of Diabetes and Digestive and Kidney Diseases
National Institute of General Medical Sciences
Publisher
Oxford University Press (OUP)
Subject
Biochemistry
Link
http://academic.oup.com/glycob/article-pdf/26/11/1198/24324403/cww043.pdf
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3. Insulin rescues retinal neurons from apoptosis by a phosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3;Barber;J Biol Chem,2001
4. A role for nuclear factor kappaB in the antiapoptotic function of insulin;Bertrand;J Biol Chem,1998
5. A mutation in a ganglioside biosynthetic enzyme, ST3GAL5, results in salt & pepper syndrome, a neurocutaneous disorder with altered glycolipid and glycoprotein glycosylation;Boccuto;Hum Mol Genet,2014
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