Interaction profile of galectin-5 with free saccharides and mammalian glycoproteins: probing its fine specificity and the effect of naturally clustered ligand presentation

Author:

Wu Albert M.,Singh Tanuja,Wu June H.,Lensch Martin,André Sabine,Gabius Hans-Joachim

Publisher

Oxford University Press (OUP)

Subject

Biochemistry

Reference85 articles.

1. Ahmad, N. , Gabius, H.-J., André, S., Kaltner, H., Sabesan, S., Roy, R., Liu, B., Macaluso, F., and Brewer, C.F. (2004) Galectin-3 precipitates as a pentamer with synthetic multivalent carbohydrates and forms heterogeneous cross-linked complexes. J. Biol. Chem., 279, 10841–10847.

2. Allen, P.Z. and Kabat, E.A. (1959) Immunochemical studies on blood groups XXII. Immunochemical studies on the nondialyzable residue from partially hydrolyzed blood group A, B, and O(H) substances (P1 fraction). J. Immunol., 82, 340–357.

3. André, S. , Kaltner, H., Lensch, M., Russwurm, R., Siebert, H.-C., Fallsehr, C., Tajkhorshid, E., Heck, A.J.R., von Knebel Doeberitz, M., Gabius, H.-J., and Kopitz, J. (2005) Determination of structural and functional overlap/divergence of five proto-type galectins by analysis of the growth-regulatory interaction with ganglioside GM1in silico and in vitro on human neuroblastoma cells. Int. J. Cancer, 114, 46–57.

4. André, S. , Kojima, S., Gundel, G., Russwurm, R., Schratt, X., Unverzagt, C., and Gabius, H.-J. (Forthcoming) Branching mode in complex-type triantennary N-glycans as regulatory element of their ligand properties. Biochim. Biophys. Acta.

5. André, S. , Kojima, S., Prahl, I., Lensch, M., Unverzagt, C., and Gabius, H.-J. (2005) Introduction of extended LEC14-type branching into core-fucosylated biantennary N-glycan. Glycoengineering for enhanced cell binding and serum clearance of the neoglycoprotein. FEBS J., 272, 1986–1998.

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