AB-type lectin (toxin/agglutinin) from mistletoe: differences in affinity of the two galactoside-binding Trp/Tyr-sites and regulation of their functionality by monomer/dimer equilibrium

Author:

Jiménez Marta,André Sabine,Siebert Hans-C.,Gabius Hans-J.,Solís Dolores

Publisher

Oxford University Press (OUP)

Subject

Biochemistry

Reference64 articles.

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2. André, S. , Cejas Ortega, P.J., Perez, M.A., Roy, R., and Gabius, H.-J. (1999) Lactose-containing starburst dendrimers: influence of dendrimer generation and binding-site orientation of receptors (plant/animal lectins and immunoglobulins) on binding properties. Glycobiology, 9, 1253–1261.

3. André, S. , Kaltner, H., Furuike, T., Nishimura, S.-I., and Gabius, H.-J. (2004) Persubstituted cyclodextrin-based glycoclusters as inhibitors of protein–carbohydrate recognition using purified plant and mammalian lectins and wild-type and lectin-gene-transfected tumor cells as targets. Bioconjug. Chem., 15, 87–98.

4. André, S. , Kaltner, H., Lensch, M., Russwurm, R., Siebert, H.-C., Fallsehr, C., Tajkhorshid, E., Heck, A.J.R., von Knebel Doeberitz, M., Gabius, H.-J., and Kopitz, J. (2005) Determination of structural and functional overlap/divergence of five proto-type galectins by analysis of the growth-regulatory interaction with ganglioside GM1in silico and in vitro on human neuroblastoma cells. Int. J. Cancer, 114, 46–57.

5. André, S. , Kojima, S., Gundel, G., Russwurm, R., Schratt, X., Unverzagt, C., and Gabius, H.-J. (2006) Branching mode in complex-type triantennary N-glycans as regulatory element of their ligand properties. Biochim. Biophys. Acta, 1760, 768–782.

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