Expression of the osteoarthritis-associated gene GDF5 is modulated epigenetically by DNA methylation

Author:

Reynard Louise N.,Bui Catherine,Canty-Laird Elizabeth G.,Young David A.,Loughlin John

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

Reference52 articles.

1. The burden of musculoskeletal conditions at the start of the new millennium: report of a WHO Scientific Group;World Health Organization Scientific Group,2003

2. A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis;Miyamoto;Nat. Genet.,2007

3. A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility;Chapman;Hum. Mol. Genet.,2008

4. Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand;Evangelou;Arthritis Rheum.,2009

5. Association of genetic and mechanical factors with age of onset of knee osteoarthritis;Ji;Zhonghua Yi Xue Yi Chuan Xue Za Zhi,2010

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