Constrained patterns of covariation and clustering of HIV-1 non-nucleoside reverse transcriptase inhibitor resistance mutations

Author:

Reuman Elizabeth C.,Rhee Soo-Yon,Holmes Susan P.,Shafer Robert W.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

Reference31 articles.

1. Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition;Sarafianos;J Mol Biol,2009

2. TMC278, a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTI-resistant HIV-1;Azijn;Antimicrob Agents Chemother,2010

3. Antiviral activity of RDEA806, a novel HIV non-nucleoside reverse transcriptase inhibitor, in treatment of näive HIV patients;Moyle

4. Resistance profile of etravirine: combined analysis of baseline genotypic and phenotypic data from the randomized, controlled Phase III clinical studies;Vingerhoets;AIDS,2010

5. IDX899, a novel HIV-1 NNRTI with high barrier to resistance, provides suppression of HIV viral load in treatment-naïve HIV-1-infected subjects;Zala

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