Severe methotrexate intoxication in a haemodialysis patient treated for rheumatoid arthritis

Author:

Boulanger Henri,Launay‐Vacher Vincent,Hierniaux Philippe,Fau Jean‐Baptiste,Deray Gilbert

Publisher

Oxford University Press (OUP)

Subject

Transplantation,Nephrology

Reference6 articles.

1. Jackson RC, Grindey GB. The biochemical basis for methotrexate cytotoxicity. In: Folate antagonists as Therapeutic Agents, Sirotnak FM, et al. (eds). Academic Press 1984: 289–315

2. El Miedany YM, Abubakr IH, El Baddini M. Effect of low dose methotrexate on markers of bone metabolism in patients with rheumatoid arthritis. J Rheumatol1998; 25: 2083–2087

3. Bleyer WA. The clinical pharmacology of methotrexate. Cancer1978; 41: 36–51

4. Atherton LD, Leib ES, Kaye MD. Toxic megacolon associated with methotrexate therapy. Gastroenterology1984; 86: 1583–1585

5. Doolittle GC, Simpson UM, Lindsley HB. Methotrexate‐associated, early‐onset pancytopenia in rheumatoid arthritis. Arch Intern Med1989; 149: 1430–1431

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