Effect of fluoroquinolone resistance mutation Thr-82→Ile on Clostridioides difficile fitness-Reference-Cited by-同舟云学术

Effect of fluoroquinolone resistance mutation Thr-82→Ile on Clostridioides difficile fitness

Published:2018-12-24 Issue:4 Volume:74 Page:877-884
ISSN:0305-7453
Container-title:Journal of Antimicrobial Chemotherapy
language:en
Short-container-title:

Author:

Vernon J J¹,Wilcox M H¹²,Freeman J¹²

Affiliation:

1. Healthcare-Associated Infections Research Group, Molecular Gastroenterology, Leeds Institute of Medical Research, University of Leeds, Old Medical School, Leeds General Infirmary, Leeds, UK

2. Microbiology, Leeds Teaching Hospitals Trust, Leeds, UK

Funder

Leeds Institute of Biological and Clinical Sciences

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

Link

http://academic.oup.com/jac/article-pdf/74/4/877/28078150/dky535.pdf

Reference40 articles.

1. Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficile-associated diarrhea: a cohort study during an epidemic in Quebec;Pepin;Clin Infect Dis,2005

2. A large outbreak of Clostridium difficile-associated disease with an unexpected proportion of deaths and colectomies at a teaching hospital following increased fluoroquinolone use;Muto;Infect Control Hosp Epidemiol,2005

3. A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality;Loo;N Engl J Med,2005

4. Effects of control interventions on Clostridium difficile infection in England: an observational study;Dingle;Lancet Infect Dis,2017

5. Fitness cost of fluoroquinolone resistance in clinical isolates of Pseudomonas aeruginosa differs by type III secretion genotype;Agnello;Front Microbiol,2016

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