Evaluating darunavir/ritonavir dosing regimens for HIV-positive pregnant women using semi-mechanistic pharmacokinetic modelling

Author:

Schalkwijk Stein12,ter Heine Rob1,Colbers Angela1,Capparelli Edmund3,Best Brookie M3,Cressey Tim R456,Greupink Rick2,Russel Frans G M2,Moltó José789,Mirochnick Mark10,Karlsson Mats O11,Burger David M1

Affiliation:

1. Department of Pharmacy, Radboud Institute for Health Sciences (RIHS), Radboud university medical center, Nijmegen, The Netherlands

2. Department of Pharmacology & Toxicology, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud university medical center, Nijmegen, The Netherlands

3. Skaggs School of Pharmacy and Pharmaceutical Sciences & School of Medicine, University of California San Diego, San Diego, CA, USA

4. Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand

5. Harvard T.H. Chan School of Public Health, Boston, MA, USA

6. Department of Molecular & Clinical Pharmacology, University of Liverpool, Liverpool, UK

7. Fundació Lluita contra la Sida, Hospital Universitari Germans Trias i Pujol, Badalona, Spain

8. Infectious Diseases Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain

9. Universitat Autònoma de Barcelona (UAB), Barcelona, Spain

10. Department of Pediatrics, Boston University School of Medicine, Boston, MA, USA

11. Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden

Funder

National Institute of Allergy and Infectious Diseases

National Institutes of Health

National Institute of Child Health and Human Development

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

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