Twenty-year trends in the prevalence of modifiable cardiovascular risk factors in young acute coronary syndrome patients hospitalized in Switzerland
Author:
Mahendiran Thabo1ORCID, Hoepli André2, Foster-Witassek Fabienne2ORCID, Rickli Hans3, Roffi Marco4ORCID, Eberli Franz5ORCID, Pedrazzini Giovanni6, Jeger Raban5ORCID, Radovanovic Dragana2ORCID, Fournier Stephane1ORCID, Lessing P, Hess F, Simon R, Hangartner P J, Hufschmid U, Jeger R, Altwegg L, Schönfelder A, Windecker S, Pilgrim T, Loretan P, Roethlisberger C, Evéquoz D, Mang G, Ryser D, Niedermaier G, Kistler W, Droll A, Hongler T, Stäuble S, Freiwald G, Schmid H P, Stauffer J C, Cook S, Bietenhard K, Roffi M, Oertli B, Schönenberger R, Schmidli M, Federspital B, Weiss E M, Weber K, Zender H, Steffen C, Poepping I, Hugi A, Frei J, Koltai E, Muller O, Pedrazzini G, Erne P, Cuculi F, Heimes T, Pagnamenta A, Urban P, Stettler C, Repond F, Widmer F, Heimgartner C, Polikar R, Bassetti S, Ernst S, Iselin H U, Giger M, Egger P, Kaeslin T, Frey R, Fischer A, Herren T, Flury G, Neumeier C, Girod G, Vogel R, Niggli B, Rickli H, Nossen J, Stoller U, Bächli E, Eriksson U, Fischer T, Peter M, Gasser S, Fatio R, Wyss C, Bertel O, Maggiorini M, Stähli B, Eberli F, Christen S,
Affiliation:
1. Department of Cardiology, Lausanne University Hospital , Rue du Bugnon 46, Lausanne 1011 , Switzerland 2. AMIS Plus Data Center Epidemiology, Biostatistics and Prevention Institute, University of Zurich , Zurich , Switzerland 3. Department of Cardiology, Kantonsspital St. Gallen , St. Gallen , Switzerland 4. Department of Cardiology, Geneva University Hospitals , Geneva , Switzerland 5. Department of Cardiology, Stadtspital Zurich , Zurich , Switzerland 6. Department of Cardiology, Cardiocentro Ticino , Lugano , Switzerland
Abstract
Abstract
Aims
Modifiable cardiovascular risk factors (RFs) play a key role in the development of coronary artery disease. We evaluated 20-year trends in RF prevalence among young adults hospitalized with acute coronary syndromes (ACS) in Switzerland.
Methods and results
Data were analysed from the Acute Myocardial Infarction in Switzerland (AMIS) Plus registry from 2000 to 2019. Young patients were defined as those aged <50 years. Among 58 028 ACS admissions, 7073 (14.1%) were young (median 45.6 years, IQR 42.0–48.0), of which 91.6% had at least one modifiable RF and 59.0% had at least two RFs. Smoking was the most prevalent RF (71.4%), followed by dyslipidaemia (57.3%), hypertension (35.9%), obesity (21.7%), and diabetes (10.1%). Compared with older patients, young patients were more likely to be obese (21.7% vs. 17.4%, P < 0.001) and active smokers (71.4% vs. 33.9%, P < 0.001). Among young patients, between 2000 and 2019, there was a significant increase in the prevalence of hypertension from 29.0% to 51.3% and obesity from 21.2% to 27.1% (both Ptrend < 0.001) but a significant decrease in active smoking from 72.5% to 62.5% (Ptrend = 0.02). There were no significant changes in the prevalence of diabetes (Ptrend = 0.32) or dyslipidaemia (Ptrend = 0.067).
Conclusion
Young ACS patients in Switzerland exhibit a high prevalence of RFs and are more likely than older patients to be obese and smokers. Between 2000 and 2019, RF prevalence either increased or remained stable, except for smoking which decreased but still affected approximately two-thirds of young patients in 2019. Public health initiatives targeting RFs in young adults in Switzerland are warranted.
Funder
AMIS Swiss Heart Foundation Abbott Medical (Schweiz) AG Amgen AG AstraZeneca AG Bayer (Schweiz) AG Biotronik (Schweiz) AG Boston Scientific AG B. Braun Medical AG Cordis-Cardinal Health GmbH Daiichi-Sankyo (Schweiz) AG Medtronic AG Novartis Pharma Schweiz AG Sanofi-Aventis Servier (Suisse) AG SIS Medical Distribution AG Terumo (Schweiz) AG Vascular Medical GmbH Swiss Working Group for Interventional Cardiology
Publisher
Oxford University Press (OUP)
Subject
Cardiology and Cardiovascular Medicine,Epidemiology
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
|
|