Lifestyle interventions to change trajectories of obesity-related cardiovascular risk from childhood onset to manifestation in adulthood: a joint scientific statement of the task force for childhood health of the European Association of Preventive Cardiology and the European Childhood Obesity Group

Author:

Hanssen Henner1ORCID,Moholdt Trine23ORCID,Bahls Martin45ORCID,Biffi Alessandro6,Siegrist Monika7ORCID,Lewandowski Adam J8ORCID,Biondi-Zoccai Giuseppe910ORCID,Cavarretta Elena910,Kokkvoll Ane11,Løchen Maja-Lisa12ORCID,Maestrini Viviana13ORCID,Pinto Rita Salvador14,Palermi Stefano6,Thivel David15,Wojcik Malgorzata16,Hansen Dominique1718ORCID,Van Craenenbroeck Emeline M1920,Weghuber Daniel2122,Kraenkel Nicolle232425,Tiberi Monica26

Affiliation:

1. Department of Sport, Exercise and Health, Medical Faculty, University of Basel , Grosse Allee 6, 4052 Basel , Switzerland

2. Department of Circulation and Medical Imaging, Norwegian University of Science and Technology , Trondheim , Norway

3. Women’s Clinic, St. Olavs Hospital , Trondheim , Norway

4. Department of Internal Medicine B University Medicine Greifswald, University of Greifswald , Greifswald , Germany

5. German Centre for Cardiovascular Research (DZHK), Partner Site Greifswald , Greifswald , Germany

6. Med-Ex Medicine & Exercise, Medical Partner Scuderia Ferrari , Rome , Italy

7. Department of Prevention and Sports Medicine, School of Medicine, University Hospital ‘rechts der Isar’, Technical University of Munich , Munich , Germany

8. Oxford Cardiovascular Clinical Research Facility, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford , Oxford , UK

9. Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome , Latina , Italy

10. Mediterranea Cardiocentro , Napoli , Italy

11. Department of Paediatrics, Finnmark Hospital Trust , Hammerfest , Norway

12. Department of Community Medicine, UiT The Arctic University of Norway , Tromsø , Norway

13. Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, ‘Sapienza’ University of Rome, Policlinico Umberto I , Rome , Italy

14. Ärztezentrum, Austria Campus , Vienna , Austria

15. Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions, Université Clermont Auvergne , Clermont-Ferrand , France

16. Department of Pediatric and Adolescent Endocrinology, Jagiellonian University Medical College , Krakow , Poland

17. Department of Cardiology, Heart Centre Hasselt, Jessa Hospital , Hasselt , Belgium

18. UHasselt, Faculty of Rehabilitation Sciences, BIOMED-REVAL-Rehabilitation Research Centre, Hasselt University , Hasselt , Belgium

19. Research Group Cardiovascular Diseases, GENCOR Department, University of Antwerp, Campus Drie Eiken , Antwerp , Belgium

20. Department of Cardiology, Antwerp University Hospital (UZA) , Edegem , Belgium

21. Obesity Research Unit, Paracelsus Medical University , Salzburg , Austria

22. Department of Pediatrics, Paracelsus Medical University , Salzburg , Austria

23. Deutsches Herzzentrum der Charité (DHZC), Department of Cardiology, Angiology and Intensive Care, Campus Benjamin-Franklin (CBF) , Berlin , Germany

24. German Centre for Cardiovascular Research (DZHK) , Partner site Berlin , Germany

25. Friede Springer- Cardiovascular Prevention Center @ Charité, Charite- Universitätsmedizin Berlin , Berlin , Germany

26. Department of Public Health, Azienda Sanitaria Unica Regionale Marche AV 1 , Pesaro , Italy

Abstract

Abstract There is an immediate need to optimize cardiovascular (CV) risk management and primary prevention of childhood obesity to timely and more effectively combat the health hazard and socioeconomic burden of CV disease from childhood development to adulthood manifestation. Optimizing screening programs and risk management strategies for obesity-related CV risk in childhood has high potential to change disease trajectories into adulthood. Building on a holistic view on the aetiology of childhood obesity, this document reviews current concepts in primary prevention and risk management strategies by lifestyle interventions. As an additional objective, this scientific statement addresses the high potential for reversibility of CV risk in childhood and comments on the use of modern surrogate markers beyond monitoring weight and body composition. This scientific statement also highlights the clinical importance of quantifying CV risk trajectories and discusses the remaining research gaps and challenges to better promote childhood health in a population-based approach. Finally, this document provides an overview on the lessons to be learned from the presented evidence and identifies key barriers to be targeted by researchers, clinicians, and policymakers to put into practice more effective primary prevention strategies for childhood obesity early in life to combat the burden of CV disease later in life.

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine,Epidemiology

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