An Increase in Reactive Oxygen Species by Dietary Fish Oil Coupled with the Attenuation of Antioxidant Defenses by Dietary Pectin Enhances Rat Colonocyte Apoptosis

Author:

Sanders Lisa M.1,Henderson Cara E.1,Hong Mee Young1,Barhoumi Rola2,Burghardt Robert C.2,Wang Naisyin3,Spinka Christine M.3,Carroll Raymond J.13,Turner Nancy D.1,Chapkin Robert S.1,Lupton Joanne R.1

Affiliation:

1. Faculty of Nutrition, Texas A&M University, College Station, TX 77843

2. Department of Veterinary Anatomy and Public Health, Texas A&M University, College Station, TX 77843

3. Department of Statistics, Texas A&M University, College Station, TX 77843

Publisher

Oxford University Press (OUP)

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

Reference38 articles.

1. Cancer statistics, 2004;Jemal;CA Cancer J. Clin.,2004

2. Novel approaches to the prevention of colon cancer by nutritional manipulation and chemoprevention;Reddy;Cancer Epidemiol. Biomark. Prev.,2000

3. Dietary factors in human colorectal cancer;Lipkin;Annu. Rev. Nutr.,1999

4. Fish oil blocks azoxymethane-induced rat colon tumorigenesis by increasing cell differentiation and apoptosis rather than decreasing cell proliferation;Chang;J. Nutr.,1998

5. Dietary n-3 PUFA increases the apoptotic response to 1,2-dimethylhydrazine, reduces mitosis and suppresses the induction of carcinogenesis in the rat colon;Latham;Carcinogenesis,1999

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