Is Metabolism of (R)-Ketamine Essential for the Antidepressant Effects?
Author:
Publisher
Oxford University Press (OUP)
Subject
Pharmacology (medical),Psychiatry and Mental health,Pharmacology
Link
http://academic.oup.com/ijnp/article-pdf/21/2/154/23738090/pyx120.pdf
Reference26 articles.
1. S-ketamine rapidly reverses synaptic and vascular deficits of hippocampus in genetic animal model of depression;Ardalan;Int J Neuropsychopharmacol,2017
2. Restoring mood balance in depression: ketamine reverses deficit in dopamine-dependent synaptic plasticity;Belujon;Biol Psychiatry,2014
3. Antidepressant effects of ketamine in depressed patients;Berman;Biol Psychiatry,2000
4. Activation of a ventral hippocampus-medial prefrontal cortex pathway is both necessary and sufficient for an antidepressant response to ketamine;Carreno;Mol Psychiatry,2016
5. Beyond ketamine: new approaches to the development of safer antidepressants;Chaki;Curr Neuropharmacol,2017
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2. Emergence of Ketamine as a Rapid Acting Antidepressant: Mechanistic Insights and Future Directions;Ketamine Revisited - New Insights into NMDA Inhibitors [Working Title];2021-09-10
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