1. Interventional Cardiology Unit, Cardiothoracic and Vascular Department (DICATOV), IRCCS Ospedale Policlinico San Martino , Largo R. Benzi, 10, Genova 16132 , Italy
2. Department of Internal Medicine and Medical Specialties (DiMI), Università di Genova , Viale Benedetto XV, 6, Genova 16132 , Italy
3. Department of Clinical and Molecular Medicine, Sapienza University of Rome , Rome , Italy
4. IRCCS San Raffaele , Rome , Italy