1. Department of Cardiovascular Medicine, Fondazione Policlinico Universitario A. Gemelli—IRCCS , Largo A. Gemelli 8, Rome 00168 , Italy
2. Department of Clinical and Molecular Medicine, Sapienza University of Rome , Via di Grottarossa 1035, Rome , Italy
3. IRCCS San Raffaele Roma , Via della Pisana, Rome , Italy