Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association–European Society of Cardiology

Author:

Maack Christoph1,Lehrke Michael2,Backs Johannes3,Heinzel Frank R4,Hulot Jean-Sebastien56,Marx Nikolaus2,Paulus Walter J7,Rossignol Patrick8,Taegtmeyer Heinrich9,Bauersachs Johann10,Bayes-Genis Antoni1112,Brutsaert Dirk13,Bugger Heiko14,Clarke Kieran15,Cosentino Francesco16,De Keulenaer Gilles17,Dei Cas Alessandra1819,González Arantxa20,Huelsmann Martin21,Iaccarino Guido22,Lunde Ida Gjervold23,Lyon Alexander R24,Pollesello Piero25,Rena Graham26,Riksen Niels P27,Rosano Giuseppe2829,Staels Bart30313233,van Laake Linda W34,Wanner Christoph35,Farmakis Dimitrios36,Filippatos Gerasimos36,Ruschitzka Frank37,Seferovic Petar38,de Boer Rudolf A39,Heymans Stephane404142

Affiliation:

1. Comprehensive Heart Failure Center, University Clinic Würzburg, Würzburg, Germany

2. Department of Internal Medicine I, University Hospital Aachen, Aachen, Germany

3. Department of Molecular Cardiology and Epigenetics, University of Heidelberg, Heidelberg, Germany

4. Department of Cardiology, Charité—Universitätsmedizin, Berlin, Germany

5. Paris Cardiovascular Research Center PARCC, INSERM UMR970, CIC 1418, and F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), Paris, France

6. AP-HP, Hôpital Européen Georges-Pompidou, Paris, France

7. Department of Physiology, VU University Medical Center, Amsterdam, The Netherlands

8. Inserm, Centre d’Investigations Cliniques—Plurithématique 14-33, Inserm U1116, CHRU Nancy, Université de Lorraine, and F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), Nancy, France

9. Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA

10. Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany

11. Heart Failure Unit and Cardiology Service, Hospital Universitari Germans Trias i Pujol, CIBERCV, Badalona, Spain

12. Department of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain

13. Prof-Emer, University of Antwerp, Antwerp, Belgium

14. Cardiology and Angiology, Heart Center, University of Freiburg, Freiburg, Germany

15. Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK

16. Department of Medicine Solna, Cardiology Unit, Karolinska Institute and Karolinska University Hospital, Stockholm, Sweden

17. Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium

18. Department of Medicine and Surgery, Endocrinology and Metabolism, University of Parma, Parma, Italy

19. Division of Endocrinology and Metabolic Diseases, Azienda Ospedaliero-Universitaria of Parma, Parma, Italy

20. Program of Cardiovascular Diseases, Centre for Applied Medical Research, University of Navarra, Pamplona and CIBERCV, Carlos III Institute of Health, Madrid, Spain

21. Division of Cardiology, Department of Medicine II, Medical University of Vienna, Vienna, Austria

22. Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, Italy

23. Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway

24. Cardiovascular Research Centre, Royal Brompton Hospital; National Heart and Lung Institute, Imperial College London, London, UK

25. Faculty of Medicine, University of Helsinki, Helsinki, Finland

26. Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK

27. Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands

28. Cardiovascular Clinical Academic Group, St George's Hospitals NHS Trust University of London, London, UK

29. IRCCS San Raffaele Roma, Rome, Italy

30. University of Lille—EGID, Lille, France

31. Inserm, U1011, Lille, France

32. Institut Pasteur de Lille, Lille, France

33. University Hospital CHU Lille, Lille, France

34. Department of Cardiology, Heart and Lungs Division, and Regenerative Medicine Centre, University Medical Centre Utrecht, Utrecht, the Netherlands

35. Würzburg University Clinic, Würzburg, Germany

36. Heart Failure Unit, Athens University Hospital Attikon, National and Kapodistrian University of Athens, Athens, Greece

37. University Heart Centre, University Hospital Zurich, Zurich, Switzerland

38. Department of Cardiology, Belgrade University Medical Centre, Belgrade, Serbia

39. Department of Cardiology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands

40. Department of Cardiology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands

41. Netherlands Heart Institute, Utrecht, The Netherlands

42. Department of Cardiovascular Sciences, Leuven University, Belgium

Funder

Deutsche Forschungsgemeinschaft

German Federal Ministry of Education and Science

Corona foundation

DFG

DZHK

German Centre for Cardiovascular Research

SFB TRR 219M-03

Netherlands Heart Foundation

Netherlands Organization for Scientific Research

National Institutes of Health

US Public Health Service

Ministerio de Educación y Ciencia

Fundació La MARATÓ de TV3

CIBER Cardiovascular

European Union Commission’s FP7 programme

MRC

European Union Commission’s Seventh Framework programme

Netherlands Cardiovascular Research Initiative

Dutch Heart Foundation

Ministry of Economic Affairs

Top Sector Life sciences & Health

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

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