Impact of lesion complexity on peri-procedural adverse events and the benefit of potent intravenous platelet adenosine diphosphate receptor inhibition after percutaneous coronary intervention: core laboratory analysis from 10 854 patients from the CHAMPION PHOENIX trial

Author:

Stone Gregg W12,Généreux Philippe234,Harrington Robert A5,White Harvey D6,Gibson C Michael7,Steg P Gabriel8,Hamm Christian W9,Mahaffey Kenneth W5,Price Matthew J10,Prats Jayne11,Deliargyris Efthymios N12,Bhatt Deepak L13

Affiliation:

1. NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY, USA

2. Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA

3. Gagnon Cardiovascular Institute, Morristown Medical Center, Morristown, NJ, USA

4. Hôpital du Sacré-Coeur de Montréal, Montréal, QC, Canada

5. Stanford University School of Medicine, Stanford, CA, USA

6. Cardiovascular Department, Auckland City Hospital, University of Auckland, New Zealand

7. Beth Israel Deaconess Medical Center, Boston, MA, USA

8. Université Paris-Diderot, Sorbonne Paris Cité, INSERM U-1148, DHU FIRE, Hopital Bichat, Assistance Publique-Hopitaux de Paris, Paris, France

9. Kerckhoff Clinic and Thoraxcenter of the University of Giessen, Bad Nauheim, Germany

10. Scripps Clinic, La Jolla, CA, USA

11. Elysis, Carlisle, MA, USA

12. Science and Strategy Consulting Group, Basking Ridge, NJ, USA

13. Brigham and Women’s Hospital Heart & Vascular Center, Harvard Medical School, Boston, MA, USA

Funder

The Medicines Company

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

Reference19 articles.

1. Re-evaluating risk factors for periprocedural complications during percutaneous coronary intervention in patients with unstable angina/non-ST-elevation myocardial infarction: who may benefit from more intensive antiplatelet therapy?;Cohen;Curr Opin Cardiol,2009

2. Prognostic impact of periprocedural bleeding and myocardial infarction after percutaneous coronary intervention in unselected patients: results from the EVENT (evaluation of drug-eluting stents and ischemic events) registry;Lindsey;JACC Cardiovasc Interv,2009

3. Impact of the angiographic mechanisms underlying periprocedural myocardial infarction after drug-eluting stent implantation;Park;Am J Cardiol,2014

4. Predictors of periprocedural (type IVa) myocardial infarction, as assessed by frequency-domain optical coherence tomography;Porto;Circ Cardiovasc Interv,2012

5. Peri-procedural myocardial injury during percutaneous coronary intervention: an important target for cardioprotection;Babu;Eur Heart J,2011

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