1. Department of Medicine, The Johns Hopkins Hospital, Baltimore, MD, USA
2. Columbia University Medical Center/New York-Presbyterian Hospital and the Cardiovascular Research Foundation, New York, NY, USA
3. Johns Hopkins Division of Cardiology, Department of Medicine, The Johns Hopkins Hospital, Baltimore, MD, USA *Corresponding author. Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Division of Cardiology, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Blalock 524C, Baltimore, MD 21287, USA. Tel: +1 410 955 5857 (office), Fax: 410-367-2151,