1. Interventional Cardiology Unit, Cardiothoracic and Vascular Department (DICATOV), IRCCS Ospedale Policlinico San Martino , Viale Benedetto XV, Genova 6–16132 , Italy
2. Department of Internal Medicine and Medical Specialties (DIMI), Università di Genova , Viale Benedetto XV, Genova 6–16132 , Italy
3. Department of Pharmacology, Catholic University School of Medicine , Largo F. Vito, 8, 00168 Rome , Italy