1. Department of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale (EOC), Via Tesserete 48 , 6900, Lugano , Switzerland
2. The Faculty of Biomedical Sciences, University of Italian Switzerland , via Giuseppe Buffi 13, 6900, Lugano , Switzerland
3. The University of Bern , Freiburgstrasse 20, 3010, Bern , Switzerland