Proposed Standardized Neurological Endpoints for Cardiovascular Clinical Trials

Author:

Lansky Alexandra J123,Messé Steven R4,Brickman Adam M5,Dwyer Michael6,Bart van der Worp H7,Lazar Ronald M5,Pietras Cody G12,Abrams Kevin J8,McFadden Eugene9,Petersen Nils H10,Browndyke Jeffrey11,Prendergast Bernard12,Ng Vivian G12,Cutlip Donald E13,Kapadia Samir14,Krucoff Mitchell W15,Linke Axel16,Scala Moy Claudia17,Schofer Joachim18,van Es Gerrit-Anne19,Virmani Renu20,Popma Jeffrey21,Parides Michael K21,Kodali Susheel22,Bilello Michel23,Zivadinov Robert6,Akar Joseph1,Furie Karen L24,Gress Daryl25,Voros Szilard26,Moses Jeffrey22,Greer David10,Forrest John K1,Holmes David27,Kappetein Arie P28,Mack Michael29,Baumbach Andreas3

Affiliation:

1. Division of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut

2. Yale Cardiovascular Research Group, New Haven, Connecticut

3. Department of Cardiology, St Bartholomew’s Hospital, William Harvey Research Institute, and Queen Mary University of London, London, United Kingdom

4. Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

5. Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York

6. Buffalo Neuroimaging Analysis, University of Buffalo, Buffalo, New York

7. Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands

8. Baptist Cardiac and Vascular Institute, Baptist Hospital of Miami, Miami, Florida

9. Department of Cardiology, Cork University Hospital, Cork, Ireland

10. Department of Neurology, Yale University School of Medicine, New Haven, Connecticut

11. Division of Geriatric Behavioral Health, Department of Psychiatry & Behavioral Sciences, Duke University Medical Center, Durham, North Carolina

12. Department of Cardiology, St. Thomas’ Hospital, London, United Kingdom

13. Division of Cardiovascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts

14. Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio

15. Department of Cardiology, Duke University Medical Center, Durham, North Carolina

16. Department of Internal Medicine/Cardiology, University of Leipzig, Leipzig, Germany

17. Office of Clinical Research, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland

18. Medicare Center and Department for Percutaneous Interventions of Structural Heart Disease, Albertine Heart Center, Hamburg, Germany

19. Cardialysis, Rotterdam, the Netherlands

20. CVpath Institute, Gaithersburg, Maryland

21. Icahn School of Medicine at Mount Sinai Group, New York, New York

22. Division of Cardiology, Department of Internal Medicine, Columbia University Medical Center, New York, New York

23. Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

24. Department of Neurology, Rhode Island Hospital, Providence, Rhode Island

25. Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, Nebraska

26. Global Institute for Research and Global Genomics Group, Richmond, Virginia

27. Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota

28. Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, the Netherlands; and the

29. Department of Cardiovascular Surgery, The Heart Hospital Baylor Plano Research Center, Plano Texas. Grants to support travel costs, meeting rooms, and lodging for academic attendees at the San Francisco and New York meetings were provided by Boston Scientific, Edwards Lifesciences, Medtronic Corporation, St. Jude Medical, NeuroSave Inc., and Keystone Heart Ltd

Funder

Dutch Heart Foundation

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

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