The point on the treatment of arrhythmic storm

Author:

Lazzari Ludovico1,Donzelli Stefano1,Tordini Alessandra1,Parise Antonio12,Pirozzi Ciro3,Di Meo Federica14,Marallo Carmine5,Pace Vincenzo12,Marini Chiara4,Carreras Giovanni1

Affiliation:

1. SSD of Clinical and Interventional Arrhythmology, ‘S. Maria’ , Terni

2. Cardiology, University of Perugia

3. Cardiology Unit, ‘S. Maria della Pietà’ , Nola

4. SC of Cardiology, ‘S. Maria’ , Terni

5. Department of Medical Biotechnology, University of Siena

Abstract

Abstract Arrhythmic storm is a clinical emergency associated with high mortality, which requires multi-disciplinary management. Reprogramming of the implantable cardiac defibrillator (ICD) aimed at reducing shocks, adrenergic blockade using beta-blockers, sedation/anxiolysis, and blockade of the stellate ganglion represent the first simple and effective manoeuvres, but further suppression of arrhythmias with antiarrhythmics is often required. A low-risk patient (e.g. monomorphic ventricular tachycardia, functioning ICD, and haemodynamically stable) should be managed with a beta-blocker (possibly non-selective) plus amiodarone, in addition to sedation with a benzodiazepine or dexmedetomidine; in patients at greater risk (high burden and haemodynamic instability), autonomic modulation with blockade of the stellate ganglion and the addition of a second antiarrhythmic (lidocaine) should be considered. In patients refractory to these measures, with advanced heart failure, general anaesthesia with intubation and the establishment of a haemodynamic circulatory support should be considered. Ablation, performed early, appears to be superior in terms of mortality and reduction of future shocks compared with titration of antiarrhythmics.

Publisher

Oxford University Press (OUP)

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