1. Department of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli—IRCCS , Largo A. Gemelli 8, Rome 00168 , Italy
2. Department of Cardiovascular and Pulmonary Sciences, Catholic University School of Medicine , Largo F. Vito 1, Rome 00168 , Italy
3. IRCCS San Raffaele Roma , Rome , Italy
4. Department of Clinical and Molecular Medicine, Sapienza University of Rome , Rome , Italy