Management strategies for heavily calcified coronary stenoses: an EAPCI clinical consensus statement in collaboration with the EURO4C-PCR group

Author:

Barbato Emanuele1ORCID,Gallinoro Emanuele2ORCID,Abdel-Wahab Mohamed3ORCID,Andreini Daniele24ORCID,Carrié Didier5ORCID,Di Mario Carlo6ORCID,Dudek Dariusz7,Escaned Javier8ORCID,Fajadet Jean9,Guagliumi Giulio10,Hill Jonathan11,McEntegart Margaret1213,Mashayekhi Kambis14,Mezilis Nikolasos15,Onuma Yoshinobu1617,Reczuch Krzyszstof18,Shlofmitz Richard19ORCID,Stefanini Giulio20,Tarantini Giuseppe21ORCID,Toth Gabor G22,Vaquerizo Beatriz23ORCID,Wijns William24,Ribichini Flavio L25

Affiliation:

1. Department of Clinical and Molecular Medicine, Sapienza University , Via di Grottarossa n. 1035, Rome, 00189 , Italy

2. Division of University Cardiology, IRCCS Galeazzi-Sant'Ambrogio Hospital, University of Milan, Milan , Italy

3. Heart Center Leipzig at University of Leipzig , Leipzig , Germany

4. Department of Biomedical and Clinical Sciences, University of Milan, Milan , Italy

5. Service de Cardiologie B, CHU Rangueil, Université Paul Sabatier , Toulouse , France

6. Interventional Structural Cardiology Division, Department of Clinical & Experimental Medicine, Careggi University Hospital , Florence , Italy

7. Institute of Cardiology, Jagiellonian University, Collegium Medicum , Krakow , Poland

8. Hospital Clínico San Carlos IDISCC, Complutense University of Madrid , Madrid , Spain

9. Clinique Pasteur , Toulouse , France

10. IRCCS Galeazzi-Sant'Ambrogio Hospital , Milan , Italy

11. Department of Cardiology, Royal Brompton Hospital , London , UK

12. West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital , Clydebank , UK

13. British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow , Glasgow , UK

14. Department of Internal Medicine and Cardiology, MediClin Heart Institute Lahr/Baden, Lahr & Division of Cardiology and Angiology II, University Heart Center Freiburg–Bad Krozingen , Bad Krozingen , Germany

15. Cardiology Department, St Luke’s Hospital , Thessaloniki , Greece

16. Department of Cardiology, Cardiovascular Center, Fujita Health University Hospital , Toyoake , Japan

17. Department of Cardiology, National University of Ireland , Galway, Ireland

18. Institute of Heart Diseases, Wroclaw Medical University , Wroclaw , Poland

19. St Francis Hospital , Roslyn, New York , USA

20. Humanitas Clinical and Research Hospital IRCCS & Department of Biomedical Sciences, Humanitas University , Milan , Italy

21. Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua , Padua , Italy

22. University Heart Center Graz, Medical University of Graz , Graz , Austria

23. Unidad de Cardiología Intervencionista, Hospital del Mar, Universidad Autónoma de Barcelona , Barcelona , Spain

24. The Lambe Institute for Translational Medicine, The Smart Sensors Laboratory, Corrib Core Laboratory and Curam, National University of Ireland , Galway , Ireland

25. Cardiovascular Section of the Department of Medicine, University of Verona , Verona , Italy

Abstract

Abstract Since the publication of the 2015 EAPCI consensus on rotational atherectomy, the number of percutaneous coronary interventions (PCI) performed in patients with severely calcified coronary artery disease has grown substantially. This has been prompted on one side by the clinical demand for the continuous increase in life expectancy, the sustained expansion of the primary PCI networks worldwide, and the routine performance of revascularization procedures in elderly patients; on the other side, the availability of new and dedicated technologies such as orbital atherectomy and intravascular lithotripsy, as well as the optimization of the rotational atherectomy system, has increased operators’ confidence in attempting more challenging PCI. This current EAPCI clinical consensus statement prepared in collaboration with the EURO4C-PCR group describes the comprehensive management of patients with heavily calcified coronary stenoses, starting with how to use non-invasive and invasive imaging to assess calcium burden and inform procedural planning. Objective and practical guidance is provided on the selection of the optimal interventional tool and technique based on the specific calcium morphology and anatomic location. Finally, the specific clinical implications of treating these patients are considered, including the prevention and management of complications and the importance of adequate training and education.

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

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