1. Department of Cardiology, Erasmus MC University Medical Centre , Dr. Molewaterplein 40, 3015 GD Rotterdam , the Netherlands
2. Department of Medical Statistics, London School of Hygiene & Tropical Medicine , Keppel Street, London WC1E 7HT , UK
3. British Heart Foundation Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow , 126 University Place, Glasgow G12 8TA , UK
4. Division of Cardiovascular Medicine, The Ohio State University , 410 W 10th Ave, Columbus, OH 43210 , USA