Participation in a clinical trial is associated with lower mortality but not lower risk of HF hospitalization in patients with heart failure: observations from the ESC EORP Heart Failure Long-Term Registry

Author:

Kapelios Chris J1ORCID,Benson Lina2,Crespo-Leiro Maria G3ORCID,Anker Stefan D4,Coats Andrew J S5ORCID,Chioncel Ovidiu6,Filippatos Gerasimos7ORCID,Lainscak Mitja8ORCID,McDonagh Theresa9ORCID,Mebazaa Alexandre10ORCID,Metra Marco11ORCID,Piepoli Massimo F12ORCID,Rosano Giuseppe M C13ORCID,Ruschitzka Frank14ORCID,Savarese Gianluigi2ORCID,Seferovic Petar M15ORCID,Volterrani Maurizio1617ORCID,Maggioni Aldo P18ORCID,Lund Lars H2ORCID

Affiliation:

1. Department of Cardiology, Laiko General Hospital , Athens , Greece

2. Unit of Cardiology, Department of Medicine, Karolinska Institutet , Solna, S1:02, 171 76 Stockholm , Sweden

3. Unidad de Insuficiencia Cardiaca Avanzada y Trasplante Cardiaco, Complexo Hospitalario Universitario A Coruna, CHUAC, INIBIC, UDC, CIBERCV , La Coruna , Spain

4. Department of Cardiology (CVK), Berlin Institute of Health Center for Regenerative Therapies (BCRT), and German Centre for Cardiovascular Research (DZHK) Partner Site Berlin, Charité Universitätsmedizin , Berlin , Germany

5. Heart Research Institute , Sydney , Australia

6. Emergency Institute for Cardiovascular Diseases ‘Prof. C.C. Iliescu’, University of Medicine Carol Davila , Bucharest , Romania

7. Heart Failure Unit, Department of Cardiology, University Hospital Attikon, National and Kapodistrian University of Athens , Athens , Greece

8. Division of Cardiology, Murska Sobota, Murska Sobota and Faculty of Medicine, University of Ljubljana , Ljubljana , Slovenia

9. King's College Hospital , London , UK

10. Department of Anesthesia-Burn-Critical Care, UMR 942 Inserm—MASCOT, University of Paris, APHP Saint Louis Lariboisière University Hospitals , Paris , France

11. Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia , Brescia , Italy

12. Department of Biomedical Science for Health, University of Milan, Via Festa del Perdono 7, 20122 Milan, Italy, and Clinical Cardiology, IRCCS Policlinico San Donato , Via Morandi 30, 20097 San Donato Milanese, Milan , Italy

13. IRCCS San Raffaele Pisana , Rome , Italy

14. Clinic of Cardiology, University Hospital , Zürich , Switzerland

15. Faculty of Medicine, University of Belgrade , Belgrade , Serbia

16. Department of Human Science and Promotion of Quality of Life, San Raffaele Open University of Rome , Rome , Italy

17. Cardiopulmonary Department, IRCCS San Raffaele , Rome , Italy

18. ANMCO Research Center, Heart Care Foundation , Florence , Italy

Abstract

Abstract

Funder

Abbott Vascular Int

Amgen

AstraZeneca

Bayer

Boehringer Ingelheim

Boston Scientific

The Bristol-Myers Squibb and Pfizer Alliance

Daiichi-Sankyo Europe

The Alliance Daiichi-Sankyo Europe GmbH and Eli Lilly and Company

Edwards

Gedeon Richter Plc

Fondazione Internazionale Menarini

MSD

Novartis Pharma AG

ResMed

Sanofi

Servier

Vifor

Karolinska Institutet

Swedish Research Council

Swedish Heart Lung Foundation

Stockholm County Council

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

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