Identification of a targeted and testable antiarrhythmic therapy for long-QT syndrome type 2 using a patient-specific cellular model-Reference-Cited by-同舟云学术

Identification of a targeted and testable antiarrhythmic therapy for long-QT syndrome type 2 using a patient-specific cellular model

Published:2017-07-21 Issue:16 Volume:39 Page:1446-1455
ISSN:0195-668X
Container-title:European Heart Journal
language:en
Short-container-title:

Author:

Mehta Ashish¹²,Ramachandra Chrishan J A¹,Singh Pritpal¹,Chitre Anuja¹,Lua Chong Hui¹,Mura Manuela³⁴⁵,Crotti Lia⁵⁶⁷,Wong Philip⁸,Schwartz Peter J⁷,Gnecchi Massimiliano³⁴⁵⁹,Shim Winston¹¹⁰

Affiliation:

1. National Heart Research Institute Singapore, National Heart Centre Singapore, 5 Hospital Drive, Singapore 169609, Singapore

2. Cardiovascular Academic Clinical Program, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore

3. Laboratory of Experimental Cardiology for Cell and Molecular Therapy, Fondazione IRCCS, Policlinico San Matteo, Viale Golgi 19, 27100 Pavia, Italy

4. Department of Cardiothoracic and Vascular Sciences-Coronary Care Unit and Laboratory of Clinical and Experimental Cardiology, Fondazione IRCCS Policlinico San Matteo, Viale Golgi 19, 27100 Pavia, Italy

5. Department of Molecular Medicine, Unit of Cardiology, University of Pavia, Viale Golgi, 19, 27100, Pavia, Italy

6. IRCCS Istituto Auxologico Italiano, San Luca Hospital, Piazzale Brescia 20, 20149 Milan, Italy

7. IRCCS Istituto Auxologico Italiano, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, via Pier Lombardo 22, 20135 Milan, Italy

8. Department of Cardiology, National Heart Centre Singapore, 5 Hospital Drive, Singapore 169609, Singapore

9. Department of Medicine, University of Cape Town, Old main Building, J-Floor Groote Schuur Hospital Observatory Cape Town 7925, South Africa

10. Cardiovascular & Metabolic Disorders Program, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore

Funder

National Research Foundation Singapore

National Medical Research Council

SingHealth Foundation

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

Link

http://academic.oup.com/eurheartj/article-pdf/39/16/1446/24690470/ehx394.pdf

Reference34 articles.

1. The long Q-T syndrome;Schwartz;Am Heart J,1975

2. The long QT syndrome: a transatlantic clinical approach to diagnosis and therapy;Schwartz;Eur Heart J,2013

3. Long-QT syndrome: from genetics to management;Schwartz;Circ Arrhythm Electrophysiol,2012

4. Risk stratification in the long-QT syndrome;Priori;N Engl J Med,2003

5. Who are the long-QT syndrome patients who receive an implantable cardioverter-defibrillator and what happens to them? Data from the European Long-QT Syndrome Implantable Cardioverter-Defibrillator (LQTS ICD) Registry;Schwartz;Circulation,2010

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