1. Interventional Cardiology Unit, Cardiothoracic and Vascular Department (DICATOV), IRCCS Ospedale Policlinico San Martino , Largo Rosanna Benzi, 10, 16132 Genova , Italy
2. Department of Internal Medicine and Medical Specialties (DIMI), Università di Genova , Viale Benedetto XV, 6, 16132 Genova , Italy
3. Department of Cardiovascular and Pulmonary Sciences, Catholic University School of Medicine , Rome, Italy
4. Center of Excellence on Ageing, CAST, ‘G. d’Annunzio’ University School of Medicine , Chieti , Italy