1. Intensive Cardiac Care Unit, Department of Cardiovascular Medicine, Fondazione Policlinico Universitario A. Gemelli—IRCCS, Catholic University of the Sacred Heart , Largo A. Gemelli 8, Rome 00168 , Italy
2. Department of Clinical and Molecular Medicine, Sapienza University of Rome , Via di Grottarossa1035, Rome , Italy
3. IRCCS San Raffaele Roma , Via di Valcannuta 250, Rome , Italy