Anti-HERG activity and the risk of drug-induced arrhythmias and sudden death-Reference-Cited by-同舟云学术

Anti-HERG activity and the risk of drug-induced arrhythmias and sudden death

Published:2005-01-06 Issue:6 Volume:26 Page:590-597
ISSN:0195-668X
Container-title:European Heart Journal
language:en
Short-container-title:

Author:

De Bruin M.L.¹²,Pettersson M.³,Meyboom R.H.B.¹³,Hoes A.W.²,Leufkens H.G.M.¹

Affiliation:

1. 1Utrecht Institute for Pharmaceutical Sciences (UIPS), Department of Pharmacoepidemiology and Pharmacotherapy, PO Box 80082, 3508 TB Utrecht, The Netherlands

2. 2Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands

3. 3The Uppsala Monitoring Centre, Uppsala, Sweden

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

Link

http://academic.oup.com/eurheartj/article-pdf/26/6/590/23989253/ehi092.pdf

Reference17 articles.

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2. Shah RR. Pharmacogenetic aspects of drug-induced torsade de pointes: potential tool for improving clinical drug development and prescribing. Drug Saf2004;27:145–172.

3. Committee for Proprietary Medicinal Products (CPMP). Points to consider: the assessment for the potential for QT interval prolongation by non-cardiovascular medicinal products (CPMP/986/96). London: European Agency for the Evaluation of Medicinal Products, 1997.

4. Committee for Proprietary Medicinal Products (CPMP). Note for guidance on safety pharmacology studies for assessing the potential for delayed ventricular repolarization (QT interval prolongation) by human pharmaceuticals (CPMP/ICH/423/02). London: European Agency for the Evaluation of Medicinal Products, 2002.

5. Redfern WS, Carlsson L, Davis AS et al. Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development. Cardiovasc Res2003;58:32–45.

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