1. Faculty of Medical Sciences, Translational and Clinical Research Institute, Newcastle University , 4th Floor William Leech Building, Newcastle upon Tyne NE2 4HH , UK
2. Cardiovascular Care Partnership, British Cardiovascular Society , 9 Fitzroy Square, London W1T 5HW , UK
3. Cardiothoracic Centre, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust , High Heaton, Newcastle upon Tyne NE7 7DN , UK