1. Department of Cardiovascular Medicine, Fondazione Policlinico Universitario A. Gemelli—IRCCS , Largo A. Gemelli, 8 - 00168 Rome, Lazio , Italy
2. Department of Cardiovascular and Pulmonary Sciences, Catholic University School of Medicine , Largo F. Vito 1, 00168 Rome, Lazio , Italy
3. Department of Clinical and Molecular Medicine, Sapienza University of Rome and IRCCS San Raffaele Rome , Via di Grottarossa, 1035 Rome , Italy