Reperfusion therapies and in-hospital outcomes for ST-elevation myocardial infarction in Europe: the ACVC-EAPCI EORP STEMI Registry of the European Society of Cardiology-Reference-Cited by-同舟云学术

Reperfusion therapies and in-hospital outcomes for ST-elevation myocardial infarction in Europe: the ACVC-EAPCI EORP STEMI Registry of the European Society of Cardiology

Published:2021-08-14 Issue:44 Volume:42 Page:4536-4549
ISSN:0195-668X
Container-title:European Heart Journal
language:en
Short-container-title:

Author:

Zeymer Uwe¹,Ludman Peter²,Danchin Nicolas³^ORCID,Kala Petr⁴^ORCID,Laroche Cécile⁵,Sadeghi Masoumeh⁶,Caporale Roberto⁷,Shaheen Sameh Mohamed⁸^ORCID,Legutko Jacek⁹^ORCID,Iakobsishvili Zaza¹⁰,Alhabib Khalid F¹¹,Motovska Zuzana¹²^ORCID,Studencan Martin¹³^ORCID,Mimoso Jorge¹⁴^ORCID,Becker David¹⁵,Alexopoulos Dimitrios¹⁶,Kereseselidze Zviad¹⁷,Stojkovic Sinisa¹⁸^ORCID,Zelveian Parounak¹⁹,Goda Artan²⁰,Mirrakhimov Erkin²¹²²^ORCID,Bajraktari Gani²³,Al-Farhan Hasan²⁴,Šerpytis Pranas²⁵,Raungaard Bent²⁶,Marandi Toomas²⁷,Moore Alice May²⁸,Quinn Martin²⁹^ORCID,Karjalainen Pasi Paavo³⁰,Tatu-Chitolu Gabriel³¹^ORCID,Gale Chris P³²^ORCID,Maggioni Aldo P⁵³³^ORCID,Weidinger Franz³⁴,Weidinger Franz,Zeymer Uwe,Danchin Nicolas^ORCID,Ludman Peter,Sinnaeve Peter,Kala Petr^ORCID,Ferrari Roberto,Maggioni Aldo P^ORCID,Goda Artan,Zelveian Parounak,Weidinger Franz,Karamfilov Kiril,Motovska Zuzana^ORCID,Zeymer Uwe,Raungaard Bent,Marandi Toomas,Shaheen Sameh Mohamed^ORCID,Lidon Rosa-Maria,Karjalainen Pasi Paavo,Kereselidze Zviad,Alexopoulos Dimitrios,Becker David,Quinn Martin^ORCID,Iakobishvili Zaza,Al-Farhan Hasan,Sadeghi Masoumeh,Caporale Roberto,Mirrakhimov Erkin^ORCID,Serpytis Pranas,Erglis Andrejs,Kedev Sasko,Moore Alice May,Dudek Dariusz,Legutko Jacek^ORCID,Mimoso Jorge^ORCID,Tatu-Chitoiu Gabriel,Stojkovic Sinisa^ORCID,Shlyakhto Evgeny,AlHabib Khalid F,Bunc Matjaz,Studencan Martin^ORCID,Mourali Mohamed Sami,Bajraktari Gani,Konte Marème,Larras Florian,Lefrancq Elin Folkesson,Mekhaldi Souad,Laroche Cécile,Maggioni Aldo P^ORCID,Goda A,Shuka N,Pavli E,Tafaj E,Gishto T,Dibra A,Duka A,Gjana A,Kristo A,Knuti G,Demiraj A,Dado E,Hasimi E,Simoni L,Siqeca M,Sisakian H,Hayrapetyan H,Markosyan S,Galustyan L,Arustamyan N,Kzhdryan H,Pepoyan S,Zirkik A,Von Lewinski D,Paetzold S,Kienzl I,Matyas K,Neunteufl T,Nikfardjam M,Neuhold U,Mihalcz A,Glaser F,Steinwender C,Reiter C,Grund M,Hrncic D,Hoppe U,Hammerer M,Hinterbuchner L,Hengstenberg C,Delle Karth G,Lang I,Weidinger F,Winkler W,Hasun M,Kastner J,Havel C,Derntl M,Oberegger G,Hajos J,Adlbrecht C,Publig T,Leitgeb M-C,Wilfing R,Jirak P,Ho C-Y,Puskas L,Schrutka L,Spinar J,Parenica J,Hlinomaz O,Fendrychova V,Semenka J,Sikora J,Sitar J,Groch L,Rezek M,Novak M,Kramarikova P,Stasek J,Dusek J,Zdrahal P,Polasek R,Karasek J,Seiner J,Sukova N,Varvarovsky I,Lazarák T,Novotny V,Matejka J,Rokyta R,Volovar S,Belohlavek J,Motovska Z^ORCID,Siranec M,Kamenik M,Kralik R,Raungaard B,Ravkilde J,Jensen S E,Villadsen A,Villefrance K,Schmidt Skov C,Maeng M,Moeller K,Hasan-Ali H,Ahmed T A,Hassan M,ElGuindy A,Farouk Ismail M,Ibrahim Abd El-Aal A,El-sayed Gaafar A,Magdy Hassan H,Ahmed Shafie M,Nabil El-khouly M,Bendary A,Darwish M,Ahmed Y,Amin O A,AbdElHakim A,Abosaif K,Kandil H,Galal M A G,El Hefny E E,El Sayed M,Aly K,Mokarrab M,Osman M,Abdelhamid M,Mantawy S,Ali M R,Kaky S D,Khalil V A,Saraya M E A,Talaat A,Nabil M,Mounir W M,Mahmoud K,Aransa A,Kazamel G,Anwar S,Al-Habbaa A,Abd el Monem M,Ismael A,Amin Abu-Sheaishaa M,Abd Rabou M M,Hammouda T M A,Moaaz M,Elkhashab K,Ragab T,Rashwan A,Rmdan A,AbdelRazek G,Ebeid H,Soliman Ghareeb H,Farag N,Zaki M,Seleem M,Torki A,Youssef M,AlLah Nasser N A,Rafaat A,Selim H,Makram M M,Khayyal M,Malasi K,Madkour A,Kolib M,Alkady H,Nagah H,Yossef M,Wafa A,Mahfouz E,Faheem G,Magdy Moris M,Ragab A,Ghazal M,Mabrouk A,Hassan M,El-Masry M,Naseem M,Samir S,Marandi T,Reinmets J,Allvee M,Saar A,Ainla T,Vaide A,Kisseljova M,Pakosta U,Eha J,Lotamois K,Sia J,Myllymaki J,Pinola T,Karjalainen P P,Paana T,Mikkelsson J,Ampio M,Tsivilasvili J,Zurab P,Kereselidze Z,Agladze R,Melia A,Gogoberidze D,Khubua N,Totladze L,Metreveli I,Chikovani A,Eitel I,Pöss J,Werner M,Constantz A,Ahrens C,Zeymer U,Tolksdorf H,Klinger S,Sack S,Heer T,Lekakis J,Kanakakis I,Xenogiannis I,Ermidou K,Makris N,Ntalianis A,Katsaros F,Revi E,Kafkala K,Mihelakis E,Diakakis G,Grammatikopoulos K,Voutsinos D,Alexopoulos D,Xanthopoulou I,Mplani V,Foussas S,Papakonstantinou N,Patsourakos N,Dimopoulos A,Derventzis A,Athanasiou K,Vassilikos V P,Papadopoulos C,Tzikas S,Vogiatzis I,Datsios A,Galitsianos I,Koutsampasopoulos K,Grigoriadis S,Douras A,Baka N,Spathis S,Kyrlidis T,Hatzinikolaou H,Kiss R G,Becker D,Nowotta F,Tóth K,Szabó S,Lakatos C,Jambrik Z,Ruzsa J,Ruzsa Z,Róna S,Toth J,Vargane Kosik A,Toth K S B,Nagy G G,Ondrejkó Z,Körömi Z,Botos B,Pourmoghadas M,Salehi A,Massoumi G,Sadeghi M,Soleimani A,Sarrafzadegan N,Roohafza H,Azarm M,Mirmohammadsadeghi A,Rajabi D,Rahmani Y,Siabani S,Najafi F,Hamzeh B,Karim H,Siabani H,Saleh N,Charehjoo H,Zamzam L,Al-Temimi G,Al-Farhan H,Al-Yassin A,Mohammad A,Ridha A,Al-Saedi G,Atabi N,Sabbar O,Mahmood S,Dakhil Z,Yaseen I F,Almyahi M,Alkenzawi H,Alkinani T,Alyacopy A,Kearney P,Twomey K,Iakobishvili Z,Shlomo N,Beigel R,Caldarola P,Rutigliano D,Sublimi Saponetti L,Locuratolo N,Palumbo V,Scherillo M,Formigli D,Canova P,Musumeci G,Roncali F,Metra M,Lombardi C,Visco E,Rossi L,Meloni L,Montisci R,Pippia V,Marchetti M F,Congia M,Cacace C,Luca G,Boscarelli G,Indolfi C,Ambrosio G,Mongiardo A,Spaccarotella C,De Rosa S,Canino G,Critelli C,Caporale R,Chiappetta D,Battista F,Gabrielli D,Marziali A,Bernabò P,Navazio A,Guerri E,Manca F,Gobbi M,Oreto G,Andò G,Carerj S,Saporito F,Cimmino M,Rigo F,Zuin G,Tuccillo B,Scotto di Uccio F,Irace L,Lorenzoni G,Meloni I,Merella P,Polizzi G M,Pino R,Marzilli M,Morrone D,Caravelli P,Orsini E,Mosa S,Piovaccari G,Santarelli A,Cavazza C,Romeo F,Fedele F,Mancone M,Straito M,Salvi N,Scarparo P,Severino P,Razzini C,Massaro G,Cinque A,Gaudio C,Barillà F,Torromeo C,Porco L,Mei M,Iorio R,Nassiacos D,Barco B,Sinagra G,Falco L,Priolo L,Perkan A,Strana M,Bajraktari G,Percuku L,Berisha G,Mziu B,Beishenkulov M,Abdurashidova T,Toktosunova A,Kaliev K,Serpytis P,Serpytis R,Butkute E,Lizaitis M,Broslavskyte M,Xuereb R G,Moore A M,Mercieca Balbi M,Paris E,Buttigieg L,Musial W,Dobrzycki S,Dubicki A,Kazimierczyk E,Tycinska A,Wojakowski W,Kalanska-Lukasik B,Ochala A,Wanha W,Dworowy S,Sielski J,Janion M,Janion-Sadowska A,Dudek D,Wojtasik-Bakalarz J,Bryniarski L,Peruga J Z,Jonczyk M,Jankowski L,Klecha A,Legutko J^ORCID,Michalowska J,Brzezinski M,Kozmik T,Kowalczyk T,Adamczuk J,Maliszewski M,Kuziemka P,Plaza P,Jaros A,Pawelec A,Sledz J,Bartus S,Zmuda W,Bogusz M,Wisnicki M,Szastak G,Adamczyk M,Suska M,Czunko P,Opolski G,Kochman J,Tomaniak M,Miernik S,Paczwa K,Witkowski A,Opolski M P,Staruch A D,Kalarus Z,Honisz G,Mencel G,Swierad M,Podolecki T,Marques J,Azevedo P,Pereira M A,Gaspar A,Monteiro S,Goncalves F,Leite L,Mimoso J^ORCID,Manuel Lopes dos Santos W,Amado J,Pereira D,Silva B,Caires G,Neto M,Rodrigues R,Correia A,Freitas D,Lourenco A,Ferreira F,Sousa F,Portugues J,Calvo L,Almeida F,Alves M,Silva A,Caria R,Seixo F,Militaru C,Ionica E,Tatu-Chitoiu G,Istratoaie O,Florescu M,Lipnitckaia E,Osipova O,Konstantinov S,Bukatov V,Vinokur T,Egorova E,Nefedova E,Levashov S,Gorbunova A,Redkina M,Karaulovskaya N,Bijieva F,Babich N,Smirnova O,Filyanin R,Eseva S,Kutluev A,Chlopenova A,Shtanko A,Kuppar E,Shaekhmurzina E,Ibragimova M,Mullahmetova M,Chepisova M,Kuzminykh M,Betkaraeva M,Namitokov A,Khasanov N,Baleeva L,Galeeva Z,Magamedkerimova F,Ivantsov E,Tavlueva E,Kochergina A,Sedykh D,Kosmachova E,Skibitskiy V,Porodenko N,Namitokov A,Litovka K,Ulbasheva E,Niculina S,Petrova M,Harkov E,Tsybulskaya N,Lobanova A,Chernova A,Kuskaeva A,Kuskaev A,Ruda M,Zateyshchikov D,Gilarov M,Konstantinova E,Koroleva O,Averkova A,Zhukova N,Kalimullin D,Borovkova N,Tokareva A,Buyanova M,Khaisheva L,Pirozhenko A,Novikova T,Yakovlev A,Tyurina T,Lapshin K,Moroshkina N,Kiseleva M,Fedorova S,Krylova L,Duplyakov D,Semenova Y,Rusina A,Ryabov V,Syrkina A,Demianov S,Reitblat O,Artemchuk A,Efremova E,Makeeva E,Menzorov M,Shutov A,Klimova N,Shevchenko I,Elistratova O,Kostyuckova O,Islamov R,Budyak V,Ponomareva E,Ullah Jan U,Alshehri A M,Sedky E,Alsihati Z,Mimish L,Selem A,Malik A,Majeed O,Altnji I,AlShehri M,Aref A,AlHabib K,AlDosary M,Tayel S,Abd AlRahman M,Asfina K N,Abdin Hussein G,Butt M,Markovic Nikolic N,Obradovic S,Djenic N,Brajovic M,Davidovic A,Romanovic R,Novakovic V,Dekleva M,Spasic M,Dzudovic B,Jovic Z,Cvijanovic D,Veljkovic S,Ivanov I,Cankovic M,Jarakovic M,Kovacevic M,Trajkovic M,Mitov V,Jovic A,Hudec M,Gombasky M,Sumbal J,Bohm A,Baranova E,Kovar F,Samos M,Podoba J,Kurray P,Obona T,Remenarikova A,Kollarik B,Verebova D,Kardosova G,Studencan M^ORCID,Alusik D,Macakova J,Kozlej M,Bayes-Genis A,Sionis A,Garcia Garcia C,Lidon R-M,Duran Cambra A,Labata Salvador C,Rueda Sobella F,Sans Rosello J,Vila Perales M,Oliveras Vila T,Ferrer Massot M,Bañeras J,Lekuona I,Zugazabeitia G,Fernandez-Ortiz A,Viana Tejedor A,Ferrera C,Alvarez V,Diaz-Castro O,Agra-Bermejo R M,Gonzalez-Cambeiro C,Gonzalez-Babarro E,Domingo-Del Valle J,Royuela N,Burgos V,Canteli A,Castrillo C,Cobo M,Ruiz M,Abu-Assi E,Garcia Acuna J M,

Affiliation:

1. Klinikum der Stadt Ludwigshafen and Institut für Herzinfarktforschung, Bremserstraße 79, 67063 Ludwigshafen am Rhein, Germany

2. Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston 1, Birmingham, B15 2TT, United Kingdom

3. Hôpital Européen Georges Pompidou, Service de Cardiologie, 20 Rue Leblanc, 75015 Paris, France

4. University Hospital Brno, Medical Faculty of Masaryk University, Dept of Internal Medicine and Cardiology, Kamenice 5, 625 00 Bohunice, Brno, Czech Republic

5. EURObservational Research Programme, European Society of Cardiology, European Heart House, 2035 Route des Colles, Sophia Antipolis, France

6. Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Shahid Rahmani Alley, Moshtagh Sevom Street, Isfahan, Iran

7. Interventional Cardiology Unit, Annunziata Civil Hospital, Via Migliori 1, 87100 Cosenza, Italy

8. Ain shams University, Ramsis Street, Abbassia Square, Cairo, Egypt

9. Jagiellonian University Medical College; Institute of Cardiology, Department of Interventional Cardiology, John Paul II Hospital, Prądnicka 80, 31-202 Kraków, Poland

10. Rabin Medical Center, Zeev Jabotinsky St 39, Petah Tikva, 49100 Israel

11. Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia

12. Cardiocenter, Third Faculty of Medicine Charles Univ. and Univ. Hospital Kralovske Ruská 2411, 100 00 Praha 10-Vinohrady, Czech Republic

13. Teaching Hospital of J.A. Reiman, Cardiocentre Prešov, Jána Hollého 5898/14, 081 81 Prešov, Slovakia

14. Centro Hospitalar e Universitário do Algarve, R. Leao Penedo, 8000-386 Faro, Portugal

15. Deputy-Director of the Heart and Vascular Center of Semmelweis University, Gaál József út 9, 1122 Budapest, Hungary

16. National and Kapodistrian University of Athens, Attikon University Hospital, Rimini 1, Chaidari 124 62, Greece

17. Chapidze Emergency Cardiology Center, 0159, Didube-Chugureti District, Nino Javakhishvili str., Tbilisi, Georgia

18. Faculty of Medicine, University of Belgrade, Belgrade, Serbia. Department of Cardiology, Clinical Center of Serbia, Pasterova 2, Beograd 11000 Belgrade, Serbia

19. Scientific Research Institute of Cardiology named after Levon Hovhannisyan, 0014, Yerevan, Paruyr Sevaki St., 5 Building (Kanaker-Zeytun adm. district), Yerevan, Armenia

20. Cardiology I & Cardiology II, University Hospital Center Mother Theresa, Rruga e Dibrës 372 Tirana AL, 1000, Albania

21. Kyrgyz State Medical Academy, 92 Akhunbayev St, Bishkek, Kyrgyzstan

22. National Center of Cardiology and Internal Medicine, Togolok Moldo Str., 720040, Bishkek, Kyrgyzstan

23. Medical Faculty, University of Prishtina "Hasan Prishtina", University Clinical Centre of Kosova, Pristina 10000, Kosovo

24. Iraqi Scientific Council of Cardiology, Baghdad Heart Center, Medical City, Baghdad, Iraq

25. Vilnius University Faculty of Medicine Hospital Santaros Klinikos, 08406, Santariškių g. 2, Vilnius 08410, Lithuania

26. Aalborg University Hospital, Department of Cardiology, Hobrovej 18-22, 9100 Aalborg, Denmark

27. North Estonia Medical Centre, J. Sütiste tee 19, 13419 Tallinn, Estonia

28. Mater Dei Hospital, Triq Dun Karm, L-Imsida, MSD2090 Msida, Malta

29. St Vincent’s University Hospital, Merrion Rd, Dublin 4, D04 N2E0, Ireland

30. Satakunta Cental Hospital, Sairaalantie 3, 28500 Pori, Finland

31. Spitalul Clinic de Urgenta "Floreasca", Calea Floreasca 8, București 014461, Romania

32. Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds School of Medicine, Worsley Building, University of Leeds, LS2 9JT Leeds, UK

33. Maria Cecilia Hospital, GVM Care & Research, Via Corriera, 1, 48033 Cotignola RA, Italy

34. Hospital Rudolfstiftung, Juchgasse 25, 1030 Wien, Austria

Abstract

Abstract Aims The aim of this study was to determine the contemporary use of reperfusion therapy in the European Society of Cardiology (ESC) member and affiliated countries and adherence to ESC clinical practice guidelines in patients with ST-elevation myocardial infarction (STEMI). Methods and results Prospective cohort (EURObservational Research Programme STEMI Registry) of hospitalized STEMI patients with symptom onset <24 h in 196 centres across 29 countries. A total of 11 462 patients were enrolled, for whom primary percutaneous coronary intervention (PCI) (total cohort frequency: 72.2%, country frequency range 0–100%), fibrinolysis (18.8%; 0–100%), and no reperfusion therapy (9.0%; 0–75%) were performed. Corresponding in-hospital mortality rates from any cause were 3.1%, 4.4%, and 14.1% and overall mortality was 4.4% (country range 2.5–5.9%). Achievement of quality indicators for reperfusion was reported for 92.7% (region range 84.8–97.5%) for the performance of reperfusion therapy of all patients with STEMI <12 h and 54.4% (region range 37.1–70.1%) for timely reperfusion. Conclusions The use of reperfusion therapy for STEMI in the ESC member and affiliated countries was high. Primary PCI was the most frequently used treatment and associated total in-hospital mortality was below 5%. However, there was geographic variation in the use of primary PCI, which was associated with differences in in-hospital mortality.

Funder

Abbott Vascular Int

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

Link

https://academic.oup.com/eurheartj/article-pdf/42/44/4536/41361871/ehab342.pdf

Reference19 articles.

1. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation;Steg;Eur Heart J,2012

2. 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC);Roffi;Eur Heart J,2016

3. Acute myocardial infarction;Anderson;N Engl J Med,2017