The management of antiplatelet therapy in acute coronary syndrome patients with thrombocytopenia: a clinical conundrum

Author:

McCarthy Cian P1,Steg Gabriel23,Bhatt Deepak L4

Affiliation:

1. Department of Medicine, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA

2. Département Hospitalo-Universitaire FIRE, AP-HP, Hôpital Bichat, FACT (French Alliance for Cardiovascular Trials), an F-CRIN Network, Université Paris-Diderot, Sorbonne Paris-Cité, INSERM U-1148, Paris, France

3. NHLI, Imperial College, ICMS Royal Brompton Hospital, Sydney Street, London, SW3 6NP, UK

4. Brigham and Women’s Hospital Heart & Vascular Center, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

Reference16 articles.

1. 2016 ACC/AHA guideline focused update on duration of dual antiplatelet therapy in patients with coronary artery disease: A report of the american college of cardiology/american heart association task force on clinical practice guidelines: An update of the 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention, 2011 ACCF/AHA guideline for coronary artery bypass graft surgery, 2012 ACC/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease, 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction, 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes, and 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery;Levine;Circulation,2016

2. ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation, the task force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology (ESC);Steg;Eur Heart J,2012

3. Antiplatelet and anticoagulation therapy for acute coronary syndromes;Bhatt;Circ Res,2014

4. Long-term dual antiplatelet therapy for secondary prevention of cardiovascular events in the subgroup of patients with previous myocardial infarction: A collaborative meta-analysis of randomized trials;Udell;Eur Heart J,2016

5. Clinical significance of thrombocytopenia during a non-ST-elevation acute coronary syndrome. The platelet glycoprotein IIb/IIIa in unstable angina: Receptor suppression using integrilin therapy (PURSUIT) trial experience;McClure;Circulation,1999

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