Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy

Author:

Ghaemi Mohammad Sajjad1234,DiGiulio Daniel B56,Contrepois Kévin7,Callahan Benjamin58ORCID,Ngo Thuy T M910,Lee-McMullen Brittany7,Lehallier Benoit11,Robaczewska Anna56,Mcilwain David12,Rosenberg-Hasson Yael13,Wong Ronald J14,Quaintance Cecele14,Culos Anthony1,Stanley Natalie1,Tanada Athena1,Tsai Amy1,Gaudilliere Dyani1,Ganio Edward1,Han Xiaoyuan1,Ando Kazuo1,McNeil Leslie1,Tingle Martha1,Wise Paul14,Maric Ivana14,Sirota Marina1516,Wyss-Coray Tony11,Winn Virginia D17,Druzin Maurice L17,Gibbs Ronald17,Darmstadt Gary L14,Lewis David B14,Partovi Nia Vahid23,Agard Bruno24,Tibshirani Robert1819,Nolan Garry12,Snyder Michael P7,Relman David A5612,Quake Stephen R9,Shaw Gary M14,Stevenson David K14,Angst Martin S1,Gaudilliere Brice1,Aghaeepour Nima1

Affiliation:

1. Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA

2. Département de Mathématiques et de Génie Industriel, École Polytechnique de Montréal, QC, H3T 1J4, Canada

3. Groupe d’Études et de Recherche en Analyse des Décision (GERAD), Montréal, QC, H3T 1J4, Canada

4. Centre Interuniversitaire de Recherche sur les Réseaux d’Entreprise, la Logistique et le Transport (CIRRELT), Montréal, QC, H3T 1J4, Canada

5. Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA

6. Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA

7. Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA

8. Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA

9. Department of Bioengineering, Stanford University, Stanford, CA, USA

10. Cancer Early Detection Advanced Research Center, Knight Cancer Institute and Department of Molecular and Medical Genetics, Oregon Health Sciences University, Portland, OR, USA

11. Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA

12. Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA

13. Institute for Immunity, Transplantation and Infection, Human Immune Monitoring Center Stanford, CA, USA

14. Division of Neonatology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA

15. Institute for Computational Health Sciences, University of California San Francisco, San Francisco, CA, USA

16. Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA

17. Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA, USA

18. Departments of Biomedical Data Sciences and Statistics, Stanford University, Stanford, CA, USA

19. Department of Statistics, Stanford University School of Medicine, Stanford, CA, USA

Funder

March of Dimes Prematurity Research Center at Stanford

Bill and Melinda Gates Foundation

Department of Anesthesiology, Perioperative and Pain Medicine and Children Health Research Institute

Ovarian Cancer Research Fund

Canadian Institute of Health Research

NIH

Burrows Wellcome Fund

NOMIS Foundation

Thomas C. and Joan M. Merigan Endowment

Publisher

Oxford University Press (OUP)

Subject

Computational Mathematics,Computational Theory and Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Statistics and Probability

Reference82 articles.

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