RCSB Protein Data Bank 1D3D module: displaying positional features on macromolecular assemblies

Abstract

Abstract Motivation Mapping positional features from one-dimensional (1D) sequences onto three-dimensional (3D) structures of biological macromolecules is a powerful tool to show geometric patterns of biochemical annotations and provide a better understanding of the mechanisms underpinning protein and nucleic acid function at the atomic level. Results We present a new library designed to display fully customizable interactive views between 1D positional features of protein and/or nucleic acid sequences and their 3D structures as isolated chains or components of macromolecular assemblies. Availability and implementation https://github.com/rcsb/rcsb-saguaro-3d. Supplementary information Supplementary data are available at Bioinformatics online.