Improved pathway reconstruction from RNA interference screens by exploiting off-target effects-Reference-Cited by-同舟云学术

Improved pathway reconstruction from RNA interference screens by exploiting off-target effects

Published:2018-06-27 Issue:13 Volume:34 Page:i519-i527
ISSN:1367-4803
Container-title:Bioinformatics
language:en
Short-container-title:

Author:

Srivatsa Sumana¹²,Kuipers Jack¹²,Schmich Fabian¹²,Eicher Simone³,Emmenlauer Mario³,Dehio Christoph³,Beerenwinkel Niko¹²

Affiliation:

1. Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland

2. SIB Swiss Institute of Bioinformatics, Basel, Switzerland

3. Biozentrum, University of Basel, Basel, Switzerland

Funder

SystemsX.ch

Swiss Initiative in Systems Biology

TargetInfectX—Multi-Pronged Perturbation of Pathogen Infection in Human Cells

Swiss National Science Foundation

Publisher

Oxford University Press (OUP)

Subject

Computational Mathematics,Computational Theory and Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Statistics and Probability

Link

http://academic.oup.com/bioinformatics/article-pdf/34/13/i519/25098482/bty240.pdf

Reference33 articles.

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2. Off-target effects by siRNA can induce toxic phenotype;Fedorov;RNA,2006

3. Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans;Fire;Nature,1998

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